[A Case of Effective Chemoradiotherapy for the Treatment of Distant Recurrence of Squamous Cell Carcinoma in the Anal Canal].

Abstract

A 75-year-old woman diagnosed with squamous cell carcinoma of the anal canal was treated using chemoradiotherapy and revealed a complete response to the tumor. After 6 months of treatment, swollen para-aortic lymph nodes were found to develop. The patient received the same regimen of chemoradiotherapy again, resulting in lymph node disappearance. However, 2 months later, PET-CT revealed accumulation of FDG in the axillary and cervical lymph nodes. Chemoradiotherapy was performed for the third time. Swollen lymph nodes were found to disappear. After 12 months, para-aortic, axillary, and cervical lymph nodes developed, following which she received BSC; subsequently, she died after 38 months of the carcinoma diagnosis.

• Authors: Akira Nonogaki, Takuya Watanabe, Toru Matsui, Takashi Miwa, Yuri Tanaka, Naoki Mashita, Kiyoshi Ishigure
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 48 Issue 12 Pg. 1519-1521 (Dec 2021) ISSN: 0385-0684 [Print] Japan
• PMID: 34911923 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Anal Canal
• Anus Neoplasms (drug therapy)
• Carcinoma, Squamous Cell (therapy)
• Chemoradiotherapy
• Female
• Humans
• Lymph Nodes
• Positron Emission Tomography Computed Tomography