Abstract | PURPOSE OF REVIEW:
Familial hypercholesterolemia (FH) is a relatively common genetic disorder associated with elevated atherosclerotic risk. Dietary interventions can modulate processes associated with cardiovascular risk and potentiate the impact of pharmacological lipid-lowering therapies. This review evaluates recent findings of dietary patterns and their components on risk biomarkers in people with FH. RECENT FINDINGS: SUMMARY: Despite the strong impact of genetic variants, dietary patterns mostly low in SFA and especially the Mediterranean diet may influence risk biomarkers in FH. However, most available studies are limited by cross-sectional design, small number of study subjects and short-term follow-ups. Robust interventional studies are necessary to test the impact of dietary patterns in people with FH.
|
Authors | Luiza Antoniazi, Raquel Arroyo-Olivares, Pedro Mata, Raul D Santos |
Journal | Current opinion in lipidology
(Curr Opin Lipidol)
Vol. 33
Issue 2
Pg. 89-94
(04 01 2022)
ISSN: 1473-6535 [Electronic] England |
PMID | 34907966
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
|
Copyright | Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved. |
Chemical References |
- Biomarkers
- Cholesterol, LDL
|
Topics |
- Atherosclerosis
(epidemiology)
- Biomarkers
- Child
- Cholesterol, LDL
- Cross-Sectional Studies
- Diet, Mediterranean
- Humans
- Hyperlipoproteinemia Type II
(complications, genetics)
|