Abstract | BACKGROUND: METHODS: RESULTS: Serum levels of potassium, albumin and B12 were lower in FP patients than in BP patients. Serum potassium concentration was statistically related to albumin concentration in peritonitis patients. Univariate and multivariate binary logistic regression analysis suggested that serum level of potassium and albumin were independent risk factors of FP when compared with BP. Lower potassium and B12 levels were independently associated with higher rates of technique failure in peritonitis. CONCLUSION: These findings suggest lower serum potassium, albumin and B12 as potential oxidative stress markers of FP and raise the hypothesis that an increased level of OS could contribute to FP.KEY MESSAGESFP remains a serious complication of peritoneal dialysis (PD), with higher morbidity (1-23.8%) and mortality (2-25%), and oxidative stress plays a role in it.Our study suggested serum potassium, albumin and vitamin B12 as potential oxidative stress markers of fungal peritonitis.
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Authors | Lingling Liu, Kehang Xie, Mengmeng Yin, Xiaoqiu Chen, Binhuan Chen, Jianting Ke, Cheng Wang |
Journal | Annals of medicine
(Ann Med)
Vol. 53
Issue 1
Pg. 2132-2141
(12 2021)
ISSN: 1365-2060 [Electronic] England |
PMID | 34779336
(Publication Type: Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Antifungal Agents
- Biomarkers
- Serum Albumin
- Vitamin B 12
- Potassium
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Anti-Bacterial Agents
(therapeutic use)
- Antifungal Agents
(therapeutic use)
- Bacterial Infections
(complications)
- Biomarkers
(blood)
- Female
- Humans
- Male
- Middle Aged
- Mycoses
(blood, complications, diagnosis)
- Oxidative Stress
(physiology)
- Peritonitis
(blood, diagnosis, microbiology)
- Potassium
(blood)
- Retrospective Studies
- Risk Factors
- Serum Albumin
- Treatment Outcome
- Vitamin B 12
(blood)
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