Reactive Oxygen Species (Oxygen Radicals)

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9352 relevant articles (147 outcomes, 711 trials/studies) found for this Bio-Agent

Description: Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of signal transduction and gene expression, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.

Also Known As:

Oxygen Radicals; Active Oxygen; Oxygen Species, Reactive; Pro-Oxidants; Oxygen, Active; Pro Oxidants

Relationship Network

Bio-Agent Context: Research Results

Inorganic Chemicals: 6

Free Radicals: 5214

Reactive Oxygen Species: 9352

Superoxides: 4406

Hydroxyl Radical: 1427

Singlet Oxygen: 454

Hypochlorous Acid: 222

Peroxides: 207

Oxygen Compounds: 9

Reactive Oxygen Species: 9352

Experts

1.	Shi, Xianglin: 8 articles (06/2008 - 05/2002)
2.	Chandel, Navdeep S: 8 articles (01/2008 - 05/2002)
3.	Singh, Shivendra V: 7 articles (09/2008 - 05/2005)
4.	Touyz, Rhian M: 7 articles (06/2008 - 11/2002)
5.	Pan, Min-Hsiung: 7 articles (05/2008 - 02/2005)
6.	Yi, Jing: 6 articles (03/2008 - 02/2002)
7.	Schumacker, Paul T: 6 articles (01/2008 - 10/2002)
8.	Wartenberg, Maria: 6 articles (01/2008 - 03/2003)
9.	Sauer, Heinrich: 6 articles (01/2008 - 03/2003)
10.	Chung, Jin Mo: 5 articles (07/2008 - 09/2004)

Related Diseases

1.	Neoplasms (Cancer) 11/01/1981 - "During primate evolution, a major factor in lengthening life-span and decreasing age-specific cancer rates may have been improved protective mechanisms against oxygen radicals. " 07/01/1998 - "These results suggest low-dose gamma-ray irradiation might be effective for the prevention of and/or therapy of various reactive oxygen species-related diseases including cancer." 04/10/2004 - "Dietary docosahexaenoic acid (DHA), which integrates into tumor cell membranes, has been reported to enhance the efficacy against tumors of cytotoxic drugs that induce reactive oxygen species (ROS). " 07/01/2009 - "Increased generation of reactive oxygen species (ROS) and an altered redox status have long been observed in cancer cells, and recent studies suggest that this biochemical property of cancer cells can be exploited for therapeutic benefits. " 02/01/2009 - "In this study, we examined the effects of platycodon D on the production of reactive oxygen species (ROS) and evaluated the association of these effects with apoptotic tumor cell death using a human leukemic U937 cell line. " Order ALL the reference details at left...
2.	Ischemia 01/01/2009 - "Overall, the findings of this study were intriguing and suggest that additional experiments on length of secondary ischemia need to be performed to further characterize the importance of reactive oxygen species on flap survival." 02/01/2008 - "BACKGROUND: Many studies indicate that the production of reactive oxygen species (ROS) after renal ischemia/reperfusion (I/R) may initiate the cascade of cellular injury. " 01/01/2008 - "Gene expression studies have revealed that the increase in oxygen radicals post-ischemia triggers the expression of a number of pro-inflammatory genes. " 02/01/2007 - "There are many experimental studies made with several chemicals in the literature for decreasing the effect of reactive oxygen species after ischemia and reperfusion. " 12/01/2005 - "Previous studies have shown endothelial cell membrane depolarization and generation of reactive oxygen species (ROS) in endothelial cells with abrupt reduction in shear stress (ischemia). " Order ALL the reference details at left...
3.	DNA Damage 01/01/2002 - "CONCLUSIONS: Strain 104 is believed to grow in the presence of 28 mg l(-1) HOCl by protecting itself against HOCl by decreasing the levels of species that could react with HOCl to generate toxic reactive oxygen radicals and by improved DNA damage repair mechanisms. " 06/01/2001 - "It is postulated that the addition of medium before liquefaction could inhibit the binding of bacteria and detritus to the sperm surface and may diminish DNA damage caused by reactive oxygen species, leading to improved efficiency of fertilization. " 06/01/1993 - "The quenchers of reactive oxygen species (ROS) afforded protection against DNA damage. " 08/31/2009 - "linteus) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study. " 05/17/2009 - "The aim of this study was to assess whether microwave-induced DNA damage is basal or it is also generated through reactive oxygen species (ROS) formation. " Order ALL the reference details at left...
4.	Inflammation 01/01/1993 - "These results indicate that high-molecular-weight HA acts directly on macrophages to inhibit phagocytosis and active oxygen formation, which, in turn, ameliorates the progression of chronic inflammation." 02/01/2007 - "This review reports the functional role of SV-IV in seminal clotting exerted through the modulation of inflammation, hemostasis, and sperm protection against the damage induced by immunological or reactive oxygen species during the long journey of spermatozoa in the female genital tract." 04/01/2004 - "Low-intensity ultrahigh frequency electromagnetic radiation (42 GHz, 100 microW/cm(2)) reduces the severity of inflammation and inhibits production of active oxygen forms by inflammatory exudate neutrophils only in mice with inflammatory process. " 04/01/2009 - "Our previous study demonstrated that reactive oxygen species (ROS) released from activated blood cells contribute significantly to the increased microvessel permeability during inflammation. " 08/01/2008 - "Several studies have shown that reactive oxygen species (ROS) play a key role in initiation as well as amplification of inflammation in asthmatic airways. " Order ALL the reference details at left...
5.	Reperfusion Injury 01/01/2005 - "In our study, we aimed to compare the effects of VEC and/or HBO in ischemia-reperfusion injury induced by free oxygen radicals in an experimental rat epigastric island skin-flap model. " 10/01/1999 - "CONCLUSIONS: Results of this study showed that prophylactic administration of CAPE in ischemic condition prevents reperfusion injuries by eliminating oxygen radicals and inhibiting polymorphonuclear leukocyte infiltration. " 08/01/1993 - "In this study we used cerebral ischaemia-reperfusion injury (IRI) as an experimental model to analyse the effects of Bio-normalizer (BN, a naturally fermented health food product) on reactive oxygen species related changes in different brain regions of gerbils. " 10/01/1992 - "This study supports evidence that generation of reactive oxygen species plays a principal part in synovial hypoxic reperfusion injury and suggests vWF as a useful marker of this phenomenon." 10/01/1992 - "This study was performed to evaluate the hypothesis that oxygen radicals/lipid peroxidation are involved in reperfusion injury in humans. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Antioxidants
2.	Superoxides (Superoxide)
3.	Xanthine Oxidase
4.	Enzymes
5.	Superoxide Dismutase
6.	Hydroxyl Radical
7.	Oxygen
8.	NF-kappa B (NF-kB)
9.	Nitric Oxide (Nitrogen Monoxide)
10.	DNA (Deoxyribonucleic Acid)

Related Therapies and Procedures

1.	Transplantation (Transplant Recipients)
2.	Chemoprevention
3.	Lasers (Laser)
4.	Heterologous Transplantation (Xenotransplantation)
5.	Oral Administration

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