Abstract | BACKGROUND AND PURPOSE: METHODS: RESULTS: Patients with PSD had lower choline and betaine levels than those without PSD (p < 0.05). Compared with tertile 1, the multivariable-adjusted odds ratios (95% CIs) for tertile 3 of choline and betaine were 0.54 (0.35-0.83) and 0.59 (0.38-0.92), respectively. Per 1 SD increase in choline or betaine was associated with a 25% (95% CI 9%-37%) or an 19% (95% CI 3%-32%) decreased risk of PSD, respectively. Furthermore, the addition of choline or betaine to the established risk factors model improved the risk reclassification for PSD, as shown by an increase in the net reclassification index and integrated discrimination improvement (all p < 0.05). CONCLUSIONS:
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Authors | Mengyuan Miao, Jigang Du, Bizhong Che, Yufei Guo, Jintao Zhang, Zhong Ju, Tan Xu, Xiaoyan Zhong, Yonghong Zhang, Chongke Zhong |
Journal | European journal of neurology
(Eur J Neurol)
Vol. 29
Issue 2
Pg. 459-468
(02 2022)
ISSN: 1468-1331 [Electronic] England |
PMID | 34611955
(Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2021 European Academy of Neurology. |
Chemical References |
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Topics |
- Choline
- Depression
(etiology)
- Humans
- Ischemic Stroke
- Nutrients
- Risk Factors
- Stroke
(complications)
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