Antihypertensive Agents (Antihypertensives)

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3515 relevant articles (251 outcomes, 511 trials/studies) found for this Bio-Agent

Description: Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.

Also Known As:

Antihypertensives; Antihypertensive Drugs; Anti-Hypertensive Agents; Anti-Hypertensive Drugs; Anti-Hypertensives; Agents, Anti-Hypertensive; Agents, Antihypertensive; Anti Hypertensive Agents; Anti Hypertensive Drugs; Anti Hypertensives; Drugs, Anti-Hypertensive; Drugs, Antihypertensive

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses

Pharmacologic Actions: 49

Therapeutic Uses: 203

Cardiovascular Agents: 241

Antihypertensive Agents: 3515

Experts

1.	Mancia, Giuseppe: 4 articles (02/2008 - 12/2004)
2.	Nilsson, Peter M: 3 articles (12/2006 - 01/2005)
3.	Kikuya, Masahiro: 2 articles (04/2008 - 05/2002)
4.	Ohkubo, Takayoshi: 2 articles (04/2008 - 05/2002)
5.	Imai, Yutaka: 2 articles (04/2008 - 05/2002)
6.	Hashimoto, Junichiro: 2 articles (04/2008 - 05/2002)
7.	Cifkova, Renata: 2 articles (12/2006 - 01/2006)
8.	Kjeldsen, Sverre E: 2 articles (12/2006 - 01/2006)
9.	Olsen, Tom Skyhøj: 2 articles (10/2006 - 08/2006)
10.	Rudd, Peter: 2 articles (06/2006 - 05/2006)

Related Diseases

1.	Hypertension (High Blood Pressure) 10/01/2003 - "We conclude that the combination of event reduction from large-scale clinical trials, adequate 24 h BP reduction, and improved tolerability compared to most other classes of anti-hypertensive agents, make the ARBs a suitable initial treatment for patients with hypertension." 08/18/2007 - "Despite the availability of effective and safe antihypertensive drugs, hypertension and its concomitant risk factors remain uncontrolled in most patients." 02/01/2005 - "Although several anti-hypertensive agents have shown to be effective in the treatment of hypertension, adequate blood pressure control is not frequent in most populations. " 08/01/2001 - "It is apparent that most available classes of antihypertensive agents can be effective in the management of hypertension, if used appropriately by providers, in conjunction with optimal adherence with prescribed medications by patients." 04/01/2008 - "(1) Pharmacological management of arterial hypertension is based on antihypertensive drugs with proven efficacy on morbidity and/or mortality endpoints. " Order ALL the reference details at left...
2.	Stroke (Strokes) 06/01/2009 - "Although meta-analyses suggest that BP reduction, per se, is the most important determinant for stroke risk reduction, the question is if specific classes of antihypertensive drugs offer special protection against stroke is still controversial. " 01/01/2003 - "However, it is not known which antihypertensive agents are most effective in preventing stroke. " 08/01/1995 - "Specific alterations of the coronary circulation may account for the relative failure of antihypertensive drugs, despite their proven efficacy in other systems (e.g., stroke prevention). " 04/01/2008 - "This study shows that mention of PROGRESS therapy in the discharge summary must be improved as it is associated with a higher use of these anti-hypertensive agents 1 year after stroke/TIA." 06/01/1990 - "Antihypertensive treatment has been validated as effective in preventing strokes but often even the cheapest antihypertensive drugs are unavailable. " Order ALL the reference details at left...
3.	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 01/01/1988 - "However, not all antihypertensive drugs seem equally effective in bringing about coronary regression of left ventricular hypertrophy (LVH). " 01/01/1987 - "However, not all antihypertensive drugs seem equally effective in bringing about coronary regression of left ventricular hypertrophy. " 12/01/1985 - "However, not all antihypertensive drugs seem equally effective in bringing about coronary regression of left ventricular hypertrophy (LVH). " 05/01/1993 - "The efficacy of many antihypertensive drugs to decrease blood pressure and to reduce left ventricular hypertrophy has already been demonstrated. " 01/01/2008 - "Several recent studies have shown that the effects of antihypertensive drugs are not the same in peripheral and central arteries, fact which could account for different effects of various drugs on end-organ damage, such as regression of left ventricular hypertrophy. " Order ALL the reference details at left...
4.	Heart Failure 11/01/2003 - "Although control of blood pressure (BP) is a primary goal of therapy, evidence from several clinical trials suggests that certain antihypertensive agents provide clinical benefits independent of their effect on BP. In the recently reported Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT), an ACE inhibitor, a CCB, and an alpha-blocker reduced coronary events and mortality to a similar extent as a thiazide-type diuretic, but the diuretic reduced one or more major cardiovascular events, especially heart failure, more than the other agents. " 08/01/2009 - "Better adherence to antihypertensive agents and risk reduction of chronic heart failure." 04/01/2009 - "Compared with Italians, non-western immigrants had increased chances of starting with combined antihypertensive agents (OR: 1.2; CIs: 1.0, 1.3), of using drugs for heart failure (OR: 1.2; CIs: 1.0, 1.4) and for diabetes (OR: 1.8; CIs: 1.6, 2.1), and of interrupting antihypertensive therapy (HR: 1.1; 95% CIs: 1.0, 1.2). " 04/01/2009 - "Compared to persons at the highest income, those at the lowest income had increased chances of starting with combined antihypertensive drugs (OR: 1.1; 95% confidence intervals (CIs): 1.0, 1.2), and of using drugs for heart failure (OR:1.5; CIs:1.3, 1.6) and diabetes (OR: 1.7; CIs: 1.6, 1.9). " 04/10/2008 - "[Antihypertensive agents, heart valve operation, stem cells: can heart failure be prevented?]" Order ALL the reference details at left...
5.	Coronary Disease (Coronary Heart Disease) 02/01/2003 - "In contrast, coronary heart disease (OR 1.38, 95% CI 1.14-1.66), year of survey (1995 vs 1988: OR 1.47, 95% CI 1.19-1.82; 1997 vs 1988: OR 1.27, 95% CI 1.02-1.42), length of hospital stay (medium vs lower tertile OR 1.20, 95% CI 0.96-1.49; higher vs lower tertile OR 1.42, 95% CI 1.13-1.77), and increase in number of antihypertensive drugs prescribed (OR 1.21, 95% CI 1.02-1.42 for one drug increase) were associated with improved blood pressure control. " 01/01/2005 - "However, there is little evidence that inhibitors of the RAAS may be effective against arterial restenosis, and a possible benefit of these substances compared to other antihypertensive drugs in the primary prevention of coronary heart disease in hypertensive patients is still a matter of debate, possibly depending on the specific substance and condition being investigated. " 01/01/1992 - "Thus, there is a need for improvement in existing antihypertensive agents in terms of greater blood pressure-lowering efficacy and improved impact on coronary heart disease in younger subjects. " 05/01/1989 - "Some properties, not shared by all antihypertensive drugs, are likely to allow some protection against heart and coronary diseases. " 01/01/1988 - "Traditional antihypertensive treatment offers little protection against coronary heart disease, perhaps because antihypertensive drugs tend to be prescribed to reduce blood pressure without attention being paid to the presence of other risk factors. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)
2.	Diuretics
3.	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)
4.	Calcium
5.	Angiotensins
6.	Antihypertensive Agents (Antihypertensives)
7.	Calcium Channel Blockers (Blockers, Calcium Channel)
8.	Indapamide
9.	Losartan (Cozaar)
10.	Angiotensin Receptors (Angiotensin II Receptor)

Related Therapies and Procedures

1.	Nephrectomy
2.	Carotid Endarterectomy
3.	Drug Therapy (Chemotherapy)
4.	Renal Dialysis (Hemodialysis)
5.	Angioplasty (Angioplasties)

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