Abstract | BACKGROUND: METHODS: We compared patient-ventilator asynchronies (the overall asynchrony index and the rates of specific asynchronies) and respiratory system mechanics (respiratory-system compliance and airway resistance) during the 24 h before tracheostomy versus the 24 h after tracheostomy. We analyzed possible differences in these variables among the subjects who underwent surgical versus percutaneous tracheostomy. To compare longitudinal changes in the variables, we used linear mixed-effects models for repeated measures along time in different observation periods. A total of 920 h of mechanical ventilation were analyzed. RESULTS: Respiratory mechanics and asynchronies did not differ significantly between the 24-h periods before and after tracheostomy: compliance of the respiratory system median (IQR) (47.9 [41.3 - 54.6] mL/cm H2O vs 47.6 [40.9 - 54.3] mL/cm H2O; P = .94), airway resistance (9.3 [7.5 - 11.1] cm H2O/L/s vs 7.0 [5.2 - 8.8] cm H2O/L/s; P = .07), asynchrony index (2.0% [1.1 - 3.6%] vs 4.1% [2.3 - 7.6%]; P = .09), ineffective expiratory efforts (0.9% [0.4 - 1.8%] vs 2.2% [1.0 - 4.4%]; P = .08), double cycling (0.5% [0.3 - 1.0%] vs 0.9% [0.5 - 1.9%]; P = .24), and percentage of air trapping (7.6% [4.2 - 13.8%] vs 10.6% [5.9 - 19.2%]; P = .43). No differences in respiratory mechanics or patient-ventilator asynchronies were observed between percutaneous and surgical procedures. CONCLUSIONS:
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Authors | Enrico Lena, José Aquino-Esperanza, Josefina López-Aguilar, Rudys Magrans, Candelaria de Haro, Leonardo Sarlabous, Neus López, Jaume Montanyà, Montserrat Rué, Robert M Kacmarek, Umberto Lucangelo, Rafael Fernández, Paolo Pelosi, Lluís Blanch, Asynchronies in the Intensive Care Unit (ASYNICU) Group |
Journal | Respiratory care
(Respir Care)
Vol. 66
Issue 9
Pg. 1389-1397
(Sep 2021)
ISSN: 1943-3654 [Electronic] United States |
PMID | 34230215
(Publication Type: Journal Article)
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Copyright | Copyright © 2021 by Daedalus Enterprises. |
Topics |
- Adult
- Humans
- Lung
- Pilot Projects
- Prospective Studies
- Respiration, Artificial
- Respiratory Mechanics
- Tracheostomy
- Ventilators, Mechanical
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