Partial Splenic Embolization for Hypersplenism Associated with Steatohepatitis in a Hemodialysis Patient.

Abstract

Hypersplenism (HS) is a disorder characterized by a triad of splenomegaly, peripheral cytopenia due to premature destruction of blood cells and normocellular bone marrow. Its etiology is diverse and includes (a) primary autoimmune cytopenias, (b) secondary to congestion due to portal hypertension in cirrhosis and, other causes such asperiportal fibrosis, infections, autoimmune diseases, lymphoproliferative disorders, infiltrative diseases and hemolytic anemias. The latter diseases are common in patients with end-stage kidney disease. In severe cases, co-existence of multiple co-morbid conditions, coagulopathy of uremia and dialysis-anticoagulation, and their immunosuppressive state render surgical splenectomy at highrisk. Mid-segment partial splenic infarction and with an aim at 50%-70% splenic volume loss was shown to be a less invasive therapy for HS. In our case report, we describe its first successful trial in a hemodialysis patient with severe HS due to cirrhosis.

• Authors: Kamel El-Reshaid, Fahad Alabdulghani, Shaikha Al-Bader
• Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (Saudi J Kidney Dis Transpl) 2021 Jan-Feb Vol. 32 Issue 1 Pg. 255-260 ISSN: 1319-2442 [Print] Saudi Arabia
• PMID: 34145142 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Embolization, Therapeutic (methods)
• Fatty Liver (complications)
• Female
• Humans
• Hypersplenism (etiology, therapy)
• Renal Dialysis
• Splenic Artery