[Clinical analysis of 31 cases of esthesioneuroblastoma].

Abstract

Objective:To investigate the clinical characteristics and prognostic factors of esthesioneuroblastoma. Methods:The clinical data of 31 patients with esthesioneuroblastoma were retrospectively studied. Results:The average time from first onset to diagnosis in 31 patients was 7.84 months, among which 3 patients（9.68%） had cervical lymph node metastasis at the first visit. By the end of follow-up, there were 25 coexisting cases and 6 deaths. The mean recurrence time of 6 patients was 10.6 months. There were 6 patients with distant metastasis, including 4 patients with cervical lymph node metastasis, 1 patient with liver metastasis and 1 patient with bone metastasis. Modified Kadish stage, different treatment methods, recurrence, first diagnosis of cervical lymph node metastasis, and distant metastasis were all factors affecting the prognosis of the patients. Conclusion:The incidence of esthesioneuroblastoma is low and the comprehensive treatment of surgery combined with radiotherapy is the optimal treatment plan. Patients with low Kadish staging, surgical combined with radiotherapy, no recurrence, no initial cervical lymph node metastasis, and no distant metastasis have a better prognosis.

• Authors: Xindi He, Ying Wang
• Journal: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery (Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi) Vol. 35 Issue 4 Pg. 338-340 (Apr 2021) ISSN: 2096-7993 [Print] China
• PMID: 33794633 (Publication Type: Journal Article)
• Copyright: Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.

Topics

• Esthesioneuroblastoma, Olfactory (diagnosis, pathology, therapy)
• Humans
• Lymph Nodes (pathology)
• Nasal Cavity (pathology)
• Neoplasm Recurrence, Local (pathology)
• Neoplasm Staging
• Nose Neoplasms (diagnosis, pathology, therapy)
• Prognosis
• Retrospective Studies