Abstract | OBJECTIVES: The aim was to evaluate patterns of multimorbidity that increase the risk of institutionalization in older persons, also exploring the potential buffering effect of formal and informal care. DESIGN: Prospective cohort study. SETTING AND PARTICIPANTS: The population-based Swedish National study on Aging and Care in Kungsholmen, Stockholm, Sweden. MEASURES: In total, 2571 community-dwelling older adults were grouped at baseline according to their underlying multimorbidity patterns, using a fuzzy c-means cluster algorithm, and followed up for 6 years to test the association between multimorbidity patterns and institutionalization. RESULTS: Six patterns of multimorbidity were identified: psychiatric diseases; cardiovascular diseases, anemia, and dementia; metabolic and sleep disorders; sensory impairments and cancer; musculoskeletal, respiratory, and gastrointestinal diseases; and an unspecific pattern including diseases of which none were overrepresented. In total, 110 (4.3%) participants were institutionalized during the follow-up, ranging from 1.7% in the metabolic and sleep disorders pattern to 8.4% in the cardiovascular diseases, anemia, and dementia pattern. Compared with the unspecific pattern, only the cardiovascular diseases, anemia, dementia pattern was significantly associated with institutionalization [relative risk ratio (RRR) = 2.23; 95% confidence interval (CI) 1.07‒4.65)], after adjusting for demographic characteristics and disability status at baseline. In stratified analyses, those not receiving formal care in the psychiatric diseases pattern (RRR 3.34; 95% CI 1.20‒9.32) and those not receiving formal or informal care in the ' cardiovascular diseases, anemia, dementia' pattern (RRR 2.99; 95% CI 1.20‒7.46; RRR 2.79; 95% CI 1.16‒6.71, respectively) had increased risks of institutionalization. CONCLUSIONS AND IMPLICATIONS:
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Authors | Alessandra Marengoni, Clare Tazzeo, Amaia Calderón-Larrañaga, Albert Roso-Llorach, Graziano Onder, Alberto Zucchelli, Debora Rizzuto, Davide Liborio Vetrano |
Journal | Journal of the American Medical Directors Association
(J Am Med Dir Assoc)
Vol. 22
Issue 10
Pg. 2184-2189.e1
(10 2021)
ISSN: 1538-9375 [Electronic] United States |
PMID | 33556330
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved. |
Topics |
- Aged
- Aged, 80 and over
- Aging
- Humans
- Independent Living
- Institutionalization
- Multimorbidity
- Prospective Studies
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