Abstract | BACKGROUND: The spore-forming bacterium Bacillus anthracis causes anthrax, an often-fatal infection in animals. Therefore, a rapid and reliable strategy to decontaminate areas, humans, and livestock from B. anthracis is very critical. OBJECTIVES: METHODS: We evaluated the efficacy of sodium hypochlorite, calcium hypochlorite, and a QAC in inhibiting vegetative cells and spores of a B. anthracis surrogate. We treated a 0.1-mL vegetative cell culture or spore solution with 10 mL sanitizer. The samples were serially diluted and cultured. RESULTS: CONCLUSIONS:
Calcium hypochlorite and QAC showed better performance than sodium hypochlorite in completely eliminating vegetative cells of B. anthracis surrogate. QAC was ineffective against spores of the B. anthracis surrogate. Among the three commercial disinfectants tested, calcium hypochlorite most effectively eliminated both B. anthracis vegetative cells and spores.
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Authors | Jin Hyeok Yim, Kwang Young Song, Hyunsook Kim, Dongryeoul Bae, Jung Whan Chon, Kun Ho Seo |
Journal | Journal of veterinary science
(J Vet Sci)
Vol. 22
Issue 1
Pg. e11
(Jan 2021)
ISSN: 1976-555X [Electronic] Korea (South) |
PMID | 33522163
(Publication Type: Journal Article)
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Copyright | © 2021 The Korean Society of Veterinary Science. |
Chemical References |
- Calcium Compounds
- Disinfectants
- Quaternary Ammonium Compounds
- calcium hypochlorite
- Sodium Hypochlorite
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Topics |
- Bacillus anthracis
(drug effects)
- Calcium Compounds
(pharmacology)
- Disinfectants
(pharmacology)
- Quaternary Ammonium Compounds
(pharmacology)
- Sodium Hypochlorite
(pharmacology)
- Spores, Bacterial
(drug effects)
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