Correlation between the magnetic resonance imaging features of squamous cell carcinoma of the buccal mucosa and pathologic depth of invasion.

Abstract

OBJECTIVE:

The objective of this study was to determine correlations between magnetic resonance imaging (MRI) features including radiologic depth of invasion (r-DOI) and pathologic DOI (p-DOI) of squamous cell carcinoma of the buccal mucosa.

STUDY DESIGN:

In total, 31 lesions were retrospectively evaluated. MRI findings included detectability, buccinator muscle invasion (positive: BMI+, negative: BMI-), buccal fat pad invasion (positive: BFPI+, negative: BFPI-), and r-DOI measured on T2-weighted images (T2-DOI) and contrast-enhanced T1-weighted images (CET1-DOI). These findings were compared to the p-DOI of the tumors.

RESULTS:

The p-DOI values of undetectable lesions were smaller than those of detectable lesions (P < .001), and the cutoff value was 1 mm. BMI+ and BFPI+ lesions had significantly larger p-DOI values than the corresponding BMI- and BFPI- lesions (P < .001), with cutoff values of 5 and 6 mm, respectively. The correlation coefficient between CET1-DOI and p-DOI was 0.68 (P < .001). CET1-DOI values were larger than p-DOI (P < .001) and the average difference between them was 3.4 mm. T2-DOI was inconclusive in 50% of cases. Interobserver agreements of MRI evaluation were good to very good.

CONCLUSION:

MRI-derived parameters were useful in estimating p-DOI and may be helpful in predicting the depth of invasion of tumors and the risk of lymph node metastasis.

• Authors: Akira Baba, Koichi Masuda, Kazuhiko Hashimoto, Satoshi Matsushima, Hideomi Yamauchi, Koshi Ikeda, Masae Yamazaki, Taiki Suzuki, Satoru Ogane, Ryo Kurokawa, Mariko Kurokawa, Yoshiaki Ota, Takuji Mogami, Takeshi Nomura, Hiroya Ojiri
• Journal: Oral surgery, oral medicine, oral pathology and oral radiology (Oral Surg Oral Med Oral Pathol Oral Radiol) Vol. 131 Issue 5 Pg. 582-590 (May 2021) ISSN: 2212-4411 [Electronic] United States
• PMID: 33516643 (Publication Type: Journal Article)
• Copyright: Copyright © 2021 Elsevier Inc. All rights reserved.

Topics

• Carcinoma, Squamous Cell (diagnostic imaging, pathology)
• Humans
• Magnetic Resonance Imaging
• Mouth Mucosa (diagnostic imaging, pathology)
• Neoplasm Invasiveness (pathology)
• Neoplasm Staging
• Retrospective Studies