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Stalin's "black dog": a postmortem diagnosis.

Abstract
Undoubtedly, the two leaders who were under enormous pressure during World War II (WWII) were Winston Churchill and Joseph Stalin' since their respective countries had to sustain most of the war weight, at least in Europe. Lord Moran recounted in his memoir Winston Churchill: The Struggle for Survival that he had diagnosed a middle-aged Churchill with bipolar disorder. Churchill himself often referred to his periods of intense and prolonged depression as his "black dog." On the contrary, not much is known about Stalin's mental conditions, although in 1927 the neurologist V. M. Bekhterev, the day prior to his sudden death, upon a long examination of the leader's mental status, declared that he had found him affected by paranoia. No chemical evidence via clinical chemistry analyses was provided for the two leaders, though. We have had access to the collection of books (stored in the Russian Government Archive of Social and Political History, RGASPI, of the former Institute of Marxism and Leninism under the Central Committee of the USSR Communist Party) that Stalin was reading during WWII, with pages containing personal annotations on the margins. Upon harvesting surface material via EVA disks (ethylene-vinyl acetate studded with strong cation and anion exchangers and C8-C18 resins) and instrumental analysis via X-ray photoelectron spectroscopy, we detected lithium levels (~ 100 ± 8 ng/cm2) compatible with those present in the sweat and/or saliva of patients treated with lithium salts for curing bipolarity and paranoia or probably gout. These data are the first clear indication that Stalin was under cure for this pathology.Graphical abstract.
AuthorsGleb Zilberstein, Svetlana Zilberstein, Pier Giorgio Righetti
JournalAnalytical and bioanalytical chemistry (Anal Bioanal Chem) Vol. 412 Issue 28 Pg. 7701-7708 (Nov 2020) ISSN: 1618-2650 [Electronic] Germany
PMID32876722 (Publication Type: Historical Article, Journal Article)
Topics
  • Aged
  • Bipolar Disorder (diagnosis)
  • Famous Persons
  • History, 20th Century
  • Humans
  • Male
  • Middle Aged
  • Paranoid Disorders (diagnosis)

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