Abstract |
Acellular dermal matrix (ADM) in direct-to- implant breast cancer reconstruction is the standard of care due to superior cosmetic results and decreased capsular contracture, but can be cost prohibitive. Although more economical, using patient's own dermis ("Autoderm") instead of ADM has undescribed sterility. Sterility is essential, as bacterial contamination may cause infection and capsular contraction. This study aimed to determine the sterility and optimal decontamination protocol of Autoderm. METHODS: A prospective controlled study of 140 samples from 20 DIEP (deep inferior epigastric perforator) breast cancer reconstruction patients was performed. Seven de-epithelialized dermal samples (2 × 1 cm) per patient were collected from excess abdominal tissue (6 decontamination protocols and one control). Samples were submerged in povidone-iodine, chlorhexidine, or cefazolin/ tobramycin/ bacitracin for 15 minutes; half of the samples were agitated (150 rpm) for 15 minutes, and half were not. The control was normal saline without agitation. The solution was removed, and the tissue was sent for aerobic colony count cultures. Patient's demographic data and complications were also collected. RESULTS: CONCLUSIONS:
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Authors | Julian Diaz-Abele, Adam Padalko, Kimberly Dalke, Michal Brichacek, Edward W Buchel |
Journal | Plastic and reconstructive surgery. Global open
(Plast Reconstr Surg Glob Open)
Vol. 8
Issue 7
Pg. e2968
(Jul 2020)
ISSN: 2169-7574 [Print] United States |
PMID | 32802661
(Publication Type: Journal Article)
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Copyright | Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. |