Diagnosis and treatment of melanoma bone metastasis: A multidisciplinary approach.

Abstract

Bone is the fourth most common site of melanoma metastasis after lung, liver, and brain. Melanoma bone metastases typically occur in patients who already have widespread metastases in other organs. Current available approaches for bone metastases from melanoma include chemotherapy, radiotherapy, biological therapy, combination therapy, and surgery. In this narrative review, we describe the management of patients affected by melanoma bone metastases, discussing the diagnostic and treatment approaches as well as their impact on survival and quality of life. Despite the fact that clinical and surgical trials will be required to determine the most appropriate treatment, we do expect a newer and more important role of multidisciplinary approach in the management of melanoma patients with bone metastases in the next future.

• Authors: Antonio Caldaria, Roberta Giuffrida, Nicola di Meo, Leo Massari, Caterina Dianzani, Serafinella Patrizia Cannavò, Ferruccio Degrassi, Edoardo Casablanca, Iris Zalaudek, Claudio Conforti
• Journal: Dermatologic therapy (Dermatol Ther) Vol. 33 Issue 6 Pg. e14193 (11 2020) ISSN: 1529-8019 [Electronic] United States
• PMID: 32790189 (Publication Type: Journal Article, Review)
• Copyright: © 2020 Wiley Periodicals LLC.

Topics

• Brain Neoplasms
• Combined Modality Therapy
• Humans
• Melanoma (therapy)
• Quality of Life