Herein, we describe a rare case of neoplastic
meningitis in a 54-year-old male with a history of
colorectal cancer. He first noticed a loss of sensation in his left thigh along with
back pain. Magnetic resonance imaging showed a
tumor lesion in the cauda equina. The
tumor was surgically resected and pathologically diagnosed as a metastatic
tumor of the descending colon
cancer for which he had undergone resection a year earlier. The patient was treated with
chemotherapy using
capecitabine,
oxaliplatin, and
cetuximab. During
chemotherapy, his
tumor markers decreased and magnetic resonance imaging showed
tumor shrinkage, but he became aware of neurological symptoms such as
hearing loss,
tinnitus, and
headache. The patient's condition suddenly worsened during the 5th course of
chemotherapy and he died 5 months after the diagnosis. Neoplastic
meningitis occurs in 4-15% of patients with solid
tumors, but it is rarely seen in
colorectal cancer. It should be considered when a patient with a history of
cancer has
back pain or neurological symptoms. The progression of neoplastic
meningitis is fast and it has a poor prognosis. Diagnosis in the early stages is important to prevent progression of neurological symptoms and to provide the most effective treatment.