Association between liver targeted antiviral therapy in colorectal cancer and survival benefits: An appraisal.

Abstract

In colorectal cancer (CRC), liver metastasis remains a major contributor to the cause of cancer-related death. Putative biomarkers, therapeutic efficacy, and drug insensitivity still pose clinical challenges for metastatic CRC patients. Interestingly, previous studies indicated that tumor cells in CRC did not metastasize to the injured liver, which included hepatitis or cirrhotic liver. The benefits of antiviral therapy on hepatocellular carcinoma have also been identified. This review discusses the role of antiviral therapy on the liver. Antiviral therapy may reduce potential liver metastasis associated with CRC in several mechanistic aspects.

• Authors: Qiang Wang, Chao-Ran Yu
• Journal: World journal of clinical cases (World J Clin Cases) Vol. 8 Issue 11 Pg. 2111-2115 (Jun 06 2020) ISSN: 2307-8960 [Print] United States
• PMID: 32548140 (Publication Type: Journal Article, Review)
• Copyright: ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.