Comparison of the efficacy of nepafenac 0.1% in quiescent Behçet's uveitis and non-uveitic healthy patients after phacoemulsification surgery.

Abstract

PURPOSE:

To compare the efficacy of nepafenac on anterior chamber flare and intraocular pressure(IOP) in healthy (group 1) and uveitic eyes (group 2) undergoing cataract surgery.

METHODS:

A retrospective, consecutive case series study.

RESULTS:

Among 54 the patients, 14 had a history of uveitis. The groups were similar in age and gender. There were significant changes in flare values in both groups. When the temporal changes of flare values were compared, there was no difference between the two groups. There were no significant changes in IOP values in both group. When the temporal changes of IOP values were compared, there was no difference between the groups.

CONCLUSIONS:

Nepafenac 0.1% has been shown to be effective in suppressing inflammation after cataract surgery in uveitic eyes as well as in healthy eyes. In addition, it has been observed that it does not increase intraocular pressure in both healthy and uveitic eyes and it is safe to use with this regard.

• Authors: Mehmed Uğur Işık, Nilüfer F Yalçındağ
• Journal: International ophthalmology (Int Ophthalmol) Vol. 40 Issue 9 Pg. 2345-2351 (Sep 2020) ISSN: 1573-2630 [Electronic] Netherlands
• PMID: 32419106 (Publication Type: Journal Article)

Chemical References

• Benzeneacetamides
• Phenylacetates
• nepafenac

Topics

• Benzeneacetamides
• Cataract (complications)
• Humans
• Intraocular Pressure
• Lens Implantation, Intraocular
• Phacoemulsification
• Phenylacetates
• Postoperative Complications
• Retrospective Studies
• Uveitis (diagnosis, drug therapy, etiology)