Cataract (Cataracts)

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12734 relevant articles (628 outcomes, 1430 trials/studies) found for this Disease

Description: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Also Known As:

Cataracts; Cataracts, Membranous; Lens Opacity; Membranous Cataract; Membranous Cataracts; Opacities, Lens; Opacity, Lens; Pseudoaphakias; Cataract, Membranous; Lens Opacities; Pseudoaphakia

Relationship Network

Disease Context: Research Results

Eye Diseases: 1323

Lens Diseases: 2

Cataract: 12734

Related Diseases

1.	Glaucoma
2.	Inflammation
3.	Cataract (Cataracts)
4.	Mydriasis
5.	Open-Angle Glaucoma (Glaucoma, Open Angle)

Experts

1.	Ito, Yoshimasa: 13 articles (05/2008 - 10/2002)
2.	Lam, Dennis S C: 13 articles (11/2007 - 06/2002)
3.	Yao, Ke: 10 articles (01/2008 - 02/2002)
4.	Menapace, Rupert: 8 articles (07/2008 - 05/2003)
5.	Nagai, Noriaki: 8 articles (05/2008 - 01/2006)
6.	Vasavada, Abhay R: 8 articles (03/2008 - 06/2003)
7.	Trivedi, Rupal H: 8 articles (02/2008 - 09/2003)
8.	Wilson, M Edward: 8 articles (02/2008 - 06/2002)
9.	Yan, Hong: 8 articles (01/2008 - 12/2005)
10.	Stark, Walter J: 7 articles (10/2008 - 03/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Cataract:

1.	Lidocaine (Xylocaine)FDA LinkGeneric 05/01/2007 - "Is intracameral lidocaine really effective in cataract surgery?" 10/01/2007 - "OBJECTIVE: To assess whether preservative-free 1% lidocaine is capable of loosing the junction between the rabbit lens epithelial cells (LECs) and between the cells and capsules and is capable of destroying the LECs, in order to provide scientific basis for pursuing safe and effective drugs to eliminate LECs in cataract surgery and to prevent capsular pacification. " 05/01/1999 - "CONCLUSIONS: A single application of lidocaine 2% gel was a safe and effective alternative to multiple topical anesthetic drops for clear corneal cataract surgery. " 01/01/2009 - "Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery." 09/01/2003 - "Efficacy of 2% lidocaine injection as a topical agent in cataract surgery." Order ALL the reference details at left...
2.	Ophthalmic Solutions (Eye Drops)IBA 09/01/2009 - "CONCLUSIONS: Eyedrops containing FGLM-amide and SSSR were effective for the prevention of SPK after cataract surgery in diabetic patients." 12/01/2001 - "OBJECTIVE: To evaluate safety and antiinflammatory efficacy of placing two Surodex (Oculex Pharmaceuticals, Inc., Sunnyvale, CA) in the eye after cataract surgery in comparison with steroid eyedrops and to compare anterior versus posterior chamber placement. " 05/01/2008 - "In this study, we attempted to clarify the mechanisms of the delaying effect of DSF eye drops on cataract development in ICR/f rats. " 04/01/2005 - "The study was done on 75 patients diagnosed with cataract, treated with non-steroidal anti-inflammatory eye drops. " 06/01/2001 - "METHOD: The study is based on a randomised, controlled clinical trial in which a steroid-containing drug delivery system (DDS) was directly compared to conventional steroid eyedrops after cataract surgery. " Order ALL the reference details at left...
3.	Diclofenac (SR 38)FDA LinkGeneric 09/01/2000 - "CONCLUSION: Diclofenac sodium is as effective as topical corticosteroid and can be used as an alternative in routine postoperative treatment following uncomplicated cataract surgery." 03/01/1995 - "Two hundred consecutive patients were enrolled in a randomized, prospective clinical trial evaluating the efficacy of diclofenac sodium (Voltaren Ophthalmic) in reducing patient discomfort after cataract surgery. " 03/01/1995 - "Efficacy of diclofenac sodium solution in reducing discomfort after cataract surgery." 01/01/2009 - "Diclofenac prevents temporal increase of intraocular pressure after uneventful cataract surgery with longer operation time." 06/01/2007 - "Diclofenac prevents an early event of macular thickening after cataract surgery in patients with diabetes." Order ALL the reference details at left...
4.	Trypan Blue FDA Link 09/01/2005 - "PURPOSE: To assess the safety and efficacy of Manual Small Incision Cataract Surgery (MSICS) in cases of white cataract with the use of trypan blue as an adjunct for performing continuous curvilinear capsulorthexis (CCC). " 06/01/2009 - "OBJECTIVE: The purpose of the study was to evaluate the effect of trypan blue on intraocular pressure (IOP) after small-incision cataract surgery. " 09/01/2005 - "MATERIALS AND METHODS: Prospective observational study on 100 consecutive eyes of 100 patients with white cataract who had undergone MSICS with trypan blue assisted CCC. " 03/01/2001 - "MATERIAL AND METHODS: Twenty patients with mature cataract were enrolled in the study and opereted on after injection of trypan blue in the anterior chamber. " 06/01/2009 - "CONCLUSIONS: The use of trypan blue during small-incision cataract surgery does not have any effect on IOP during the immediate and early postoperative period." Order ALL the reference details at left...
5.	AntioxidantsIBA 01/01/2006 - "It is generally believed that prophylactic intake of antioxidants is beneficial in delaying the onset of some aging manifestations such as cataract. " 02/01/1999 - "BACKGROUND: It is not known whether the protective effects of antioxidants on cataract observed in experimental animals are relevant to age-related opacities in humans. " 06/01/2008 - "Long-term intake of antioxidants may offer protection against cataract. " 08/01/2008 - "CONCLUSIONS: Inverse associations were found between cataract and blood antioxidants in an antioxidant-depleted study sample." 04/01/2006 - "PURPOSE: To describe the methodology and baseline data for the Antioxidants in Prevention of Cataracts (APC) study in South India. " Order ALL the reference details at left...
6.	Retinaldehyde (Retinal)IBA 01/01/1983 - "Cataracts prevented us from having better information on diabetic retinae prior to treatment and a redesigned study would have to include unilateral histological retinal examination before any treatment is started to determine if, indeed, improved platelet physiology slows or reverses changes in the diabetic retina." 06/01/1993 - "The results of this study suggest that such a therapeutic attitude results in diminished cataract prevalence and decreased prevalence of vision-limiting retinal pathology, with resultant improved visual outcome of the cataract surgery which is eventually needed in a small proportion of the patients." 07/01/2009 - "The amount of VH was graded with slit lamp biomicroscopy by three masked retinal specialists from grade 0 to grade 3. Main outcome measures were rate of recurrence of the VH, improvement in visual acuity, incidence of cataract formation, and postoperative complications through a follow-up of 6 months. " 10/01/2008 - "PURPOSE: To evaluate the efficacy of Fourier analysis of digital retinal images in grading cataract severity. " 03/01/2009 - "METHODS: This is a prospective comparative interventional trial comprising of 60 eyes of 60 consecutive patients with cataract and/or vitreo-retinal pathology. " Order ALL the reference details at left...
7.	Bupivacaine (Bupivacaine Hydrochloride)FDA LinkGeneric 11/01/2004 - "Aqueous humor levels of topically applied bupivacaine 0.75% in cataract surgery." 09/01/2003 - "Aqueous humor levels of topically applied bupivacaine 0.75% in cataract surgery." 10/01/1996 - "Cataract surgery with 0.75% bupivacaine." 07/01/1992 - "Fifty patients scheduled for cataract surgery under peribulbar block were randomised to receive either plain (pH 5.4) or pH-adjusted (pH 6.8 range 6.7-6.9) 0.75% bupivacaine. " 01/01/1974 - "Bupivacaine in cataract surgery." Order ALL the reference details at left...
8.	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 12/31/1997 - "Aspirin has been associated with many beneficial effects, including protection against cataract, in-vivo. " 12/01/1997 - "Topical aspirin provides protection against galactosemic cataract." 03/01/2001 - "OBJECTIVE: To examine the effect of assigned aspirin treatment and posttrial, self-selected aspirin use on the risk of age-related cataract over the 15 years of follow-up of Physicians' Health Study I. METHODS: Participants were 20 968 US male physicians enrolled in Physicians' Health Study I who did not report cataract at baseline. " 03/01/2001 - "Aspirin use and risk of cataract in posttrial follow-up of Physicians' Health Study I." 01/01/2001 - "A variety of laboratory and epidemiological evidence supports the benefits of aspirin-like drugs but there has been no trial specifically in patients with cataract. " Order ALL the reference details at left...
9.	Mitomycin (Mitomycin-C)FDA LinkGeneric 06/01/2001 - "[The inhibitory effect of mitomycin C applied by intracapsular method on rabbit lens epithelial cells: an experimental study of after-cataract]" 12/01/1996 - "The purpose of this study was to attempt to inhibit this secondary cataract formation by using mitomycin (an antimitotic drug). " 11/01/2007 - "PURPOSE: To compare posterior capsule opacification (PCO) in rabbits who undergo cataract surgery and receive either mitomycin-C (MMC) or distilled water (DW) during sealed-capsule irrigation (SCI). " 11/01/2007 - "Comparison of posterior capsule opacification in rabbits receiving either mitomycin-C or distilled water for sealed-capsule irrigation during cataract surgery." 07/01/2002 - "If necessary, the procedure was combined with cataract surgery or mitomycin C application. " Order ALL the reference details at left...
10.	Indomethacin (Indometacin)FDA LinkGeneric 07/01/1996 - "Furthermore, indomethacin was partially protective against UVB cataract formation and lowered cataract severity from stage 3 to stage 1, but it did not prevent UVB-induced lens changes completely. " 12/01/1984 - "One hundred six consecutive patients undergoing elective cataract surgery were divided into a control group and treatment group in a double-blinded study to evaluate the non-steroidal, anti-inflammatory drug indomethacin as an aid for maintaining pupil dilation during surgery. " 07/01/1996 - "To determine the effect of inhibition of prostaglandin synthesis on UVB-induced cataract formation, animals were given indomethacin intraperitoneally. " 08/01/1992 - "The effect of indomethacin 1% ophthalmic suspension on the pupil during extracapsular cataract surgery." 01/01/1991 - "In this paper, we studied the effect of 0.1% indomethacin treatment to patients before and after cataract surgery. " Order ALL the reference details at left...

Therapies and Procedures

1.	Phacoemulsification 09/01/2002 - "CONCLUSION: It is safe and effective for highly myopic patients with cataract to implant a low or negative power Acrysof IOL after phacoemulsification." 04/01/2008 - "CONCLUSIONS: Cataract surgery performed by phacoemulsification has been proven to be effective in improving quality of life, especially in physical aspects, according to the improvement in role limitation due to physical problems. " 06/01/2003 - "CONCLUSIONS: Phacoemulsification with burst and occlude mode was very effective in the treatment of hard nucleus cataract, and was safer. " 08/01/1990 - "Improved by both technology and new surgical procedures, phacoemulsification of the nucleus has become increasingly important in extracapsular cataract surgery. " 01/01/2005 - "CONCLUSIONS: BAB breakdown following phacoemulsification with posterior chamber lens implantation is relatively mild in eyes with FHU and the BAB appears to be fully reestablished to preoperative levels 6 weeks postoperatively, explaining the usually good outcome of cataract surgery in this condition." Order ALL the reference details at left...
2.	Intraocular Lenses (Intraocular Lens) 03/01/2006 - "Use of Cionni ring helped in the successful intraocular lens (IOL) implantation in a 30-year-old patient with bilateral congenital subluxated cataracts. " 02/01/1998 - "Recent improvements in cataract surgery and intraocular lens (IOL) technology have allowed rapid improvement in quality visual acuity. " 06/01/2008 - "PURPOSE: To evaluate the efficacy of the aspheric optic of the AcrySof IQ SN60WF intraocular lens (IOL) in decreasing spherical and total higher order aberrations and improving contrast sensitivity after cataract surgery compared to the spheric AcrySof SN60AT. " 05/01/2007 - "PURPOSE: To evaluate the efficacy of AcrySof SN60WF aspheric intraocular lens (IOL) in decreasing spherical aberration and total higher order aberrations (HOAs) after cataract surgery compared to the spherical SN60AT lens. " 04/01/2007 - "Automation introduced in surgery and intraocular lenses have helped to achieve better anatomic conditions and functional outcome of cataract surgery in children." Order ALL the reference details at left...
3.	Cataract Extraction 12/01/2002 - "CONCLUSION: Subjects with various stages of dry AMD and cataract improved their self assessed visual function and satisfaction with vision significantly after cataract extraction." 05/01/2001 - "CONCLUSION: The outcome of simultaneous bilateral cataract extraction was comparable to that of single-eye cataract surgery, indicating that the procedure is safe under strict surgical protocol and beneficial in selected cases." 07/01/1989 - "Observation of our material showed that qualifying diabetic patients for cataract extraction and taking into consideration the over mentioned contraindications one can obtain good results similar as in other patients with cataract." 03/01/1996 - "CONCLUSION: The operation is a safe reliable one for restoration of visual acuity in patients with cataract, and is superior to extracapsular cataract extraction." 05/01/1989 - "Five cases had a mature cataract and had extracapsular cataract extraction; surgery restored isometropia, improved the visual acuity to 20/200 or better, and enlarged the field of vision. " Order ALL the reference details at left...
4.	Vitrectomy 09/01/2009 - "Intraoperative use of TA can visualize posterior hyaloid, preretinal membrane, internal limiting membrane (ILM) during pars plana vitrectomy, and prolapsed vitreous during cataract surgery, which can make the procedure very safe and effective. " 01/01/2003 - "Statistically significant improvement in visual acuity was observed after cataract surgery, compared to the results after vitrectomy in the study group and in the control group. " 11/01/1994 - "However, vitrectomy on the same day as cataract surgery generally yielded favorable visual acuity outcomes and eliminated the need for a second operation at a later date. " 12/01/2004 - "CONCLUSIONS: For children undergoing pediatric cataract surgery between the ages of 10 months and 7 years, IOL implantation combined with primary pars plana posterior capsulectomy and anterior vitrectomy is effective in preventing re-opacification of the visual pathway." 04/01/2009 - "CONCLUSIONS: The 25-gauge vitrectomy system appears safe and effective for the management of infantile cataract. " Order ALL the reference details at left...
5.	Intraocular Lens Implantation 12/01/1999 - "The incidence of posterior capsule opacification (PCO), the most common complication of modern cataract surgery with intraocular lens implantation, seems to have decreased slightly as a result of improved surgical and cortical cleanup techniques. " 11/01/1988 - "The authors offer their experience of intraocular lens implantation in the Torres Strait as a model for a more visually appropriate surgical cure for Third World cataract." 01/01/2008 - "CONCLUSION: Primary intraocular lens implantation in children with unilateral idiopathic cataracts is an effective treatment for visual rehabilitation. " 11/01/2006 - "CONCLUSIONS: Intraocular lens implantation for children with congenital or developing cataract is an effective treatment for visual rehabilitation, even for those patients age 2 years and younger." 10/01/2001 - "This drug is an effective and safe steroidal antiinflammatory agent for topical use following cataract surgery and intraocular lens implantation." Order ALL the reference details at left...

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