Abstract | BACKGROUND: OBJECTIVES: METHODS: RESULTS: Kinesigenic triggers, male predilection, dystonic attacks, aura, complicated forms of paroxysmal kinesigenic dyskinesia, clustering in patients with family history, and dramatic responses to antiepileptic treatment were the prominent features in this multicenter study. Clinical analysis showed that proline-rich transmembrane protein 2 mutation carriers were prone to present at a younger age and have longer attack duration, bilateral limb involvement, choreic attacks, a complicated form of paroxysmal kinesigenic dyskinesia, family history, and more forms of dyskinesia. The new high-knee-exercise test efficiently induced attacks and could assist in diagnosis. CONCLUSIONS:
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Authors | Xiao-Jun Huang, Shi-Ge Wang, Xia-Nan Guo, Wo-Tu Tian, Fei-Xia Zhan, Ze-Yu Zhu, Xiao-Meng Yin, Qing Liu, Kai-Li Yin, Xiao-Rong Liu, Yu Zhang, Zhen-Guo Liu, Xiao-Li Liu, Lan Zheng, Tian Wang, Li Wu, Tian-Yi Rong, Yan Wang, Mei Zhang, Guang-Hui Bi, Wei-Guo Tang, Chao Zhang, Ping Zhong, Chun-Yu Wang, Jian-Guang Tang, Wei Lu, Ru-Xu Zhang, Guo-Hua Zhao, Xun-Hua Li, Hua Li, Tao Chen, Hai-Yan Li, Xiao-Guang Luo, Yan-Yan Song, Hui-Dong Tang, Xing-Hua Luan, Hai-Yan Zhou, Bei-Sha Tang, Sheng-Di Chen, Li Cao |
Journal | Movement disorders : official journal of the Movement Disorder Society
(Mov Disord)
Vol. 35
Issue 8
Pg. 1428-1437
(08 2020)
ISSN: 1531-8257 [Electronic] United States |
PMID | 32392383
(Publication Type: Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)
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Copyright | © 2020 International Parkinson and Movement Disorder Society. |
Chemical References |
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Topics |
- China
- Dystonia
(genetics)
- Humans
- Male
- Mutation
(genetics)
- Nerve Tissue Proteins
(genetics)
- Phenotype
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