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Daily auricular stimulation with capsaicin ointment improved cough reflex sensitivity in elderly patients with dysphagia: a pilot study.

Abstract
Background: In our previous study, a single auricular application of capsaicin ointment, but not placebo improved cough reflex in elderly patients with dysphagia.Aims/Objectives: In the present study, we examined whether daily auricular application of capsaicin ointment continued to improve cough reflex in similar patients.Material and methods: With a cotton swab, 0.025% capsaicin ointment was applied in each external auditory canal alternately once a day for 2 weeks. The cough reflex sensitivity was evaluated on videoendoscopy using a numerical score and inhalation cough challenge test using citric acid in elderly dysphagic inpatients.Results: After daily auricular application of capsaicin ointment for 2 weeks, the endoscopic score of glottal closure and cough reflexes significantly improved, and the citric acid cough threshold significantly decreased. There was a significant correlation between the endoscopic score and the citric acid cough threshold before and after daily capsaicin application in the patients.Conclusions: Daily auricular stimulation with capsaicin ointment for 2 weeks continued to improve the cough reflex sensitivity in elderly patients with dysphagia.Significance: Daily auricular stimulation with capsaicin ointment would be a safe and effective intervention to prevent pneumonia in elderly with a risk of aspiration.
AuthorsHiroki Ohnishi, Osamu Jinnouchi, Seiji Agawa, Eiji Kondo, Ikuji Kawata, Hidehiko Okamoto, Takahiro Azuma, Go Sato, Yoshiaki Kitamura, Koji Abe, Noriaki Takeda
JournalActa oto-laryngologica (Acta Otolaryngol) Vol. 140 Issue 3 Pg. 249-253 (Mar 2020) ISSN: 1651-2251 [Electronic] England
PMID32022628 (Publication Type: Journal Article)
Chemical References
  • Ointments
  • Capsaicin
Topics
  • Aged
  • Aged, 80 and over
  • Capsaicin (administration & dosage, pharmacology)
  • Cough (drug therapy, etiology)
  • Deglutition Disorders (complications, drug therapy)
  • Ear Canal (drug effects, innervation)
  • Endoscopy
  • Female
  • Humans
  • Male
  • Ointments
  • Pilot Projects
  • Reflex (drug effects)

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