[A clinical evaluation of CS-807 in patients with urinary tract infections].

Abstract

CS-807 is a new cephalosporin orally available. The clinical efficacy and safety of this drug were evaluated in 13 patients with urinary tract infection, including 3 with simple cystitis and 10 with complicated infections. According to the response criteria defined by the Japanese UTI committee, the clinical effectiveness in 8 patients with complicated urinary tract infections regarded evaluable was excellent in 2, moderate in 4 and poor in 2, the overall efficacy rate being 75.0%. Only 1 of the 13 patients studied, developed temporary diarrhea as a drug related adverse reaction.

• Authors: K Nakajima, Y Oshinoya, T Uchibayashi, M Ohkawa, H Hisazumi
• Journal: Hinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 34 Issue 8 Pg. 1515-8 (Aug 1988) ISSN: 0018-1994 [Print] Japan
• PMID: 3195413 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Infective Agents, Urinary
• Cephalosporins
• Ceftizoxime

Topics

• Adult
• Aged
• Anti-Infective Agents, Urinary (therapeutic use)
• Ceftizoxime (analogs & derivatives)
• Cephalosporins (adverse effects, therapeutic use)
• Cystitis (drug therapy)
• Diarrhea (chemically induced)
• Drug Evaluation
• Female
• Humans
• Male
• Middle Aged
• Urinary Tract Infections (drug therapy)
• Cefpodoxime Proxetil