"Incompatible Housemates": Hypertrophic Obstructive Cardiomyopathy and Takotsubo Syndrome.

Abstract

This case report concerns an 81-year-old woman with previously well-controlled hypertrophic obstructive cardiomyopathy (HOCM). She was referred to our hospital because of the acute onset of takotsubo syndrome. Echocardiography revealed basal hyperkinesis due to takotsubo syndrome superimposed on septal hypertrophy, which resulted in the reappearance of prominent left ventricular outflow tract obstruction (LVOTO). Although she developed cardiogenic shock triggered by atrial fibrillation, LVOTO was successfully mitigated by aggressive fluid resuscitation, rhythm control, and the administration of β-blocker. We herein report a rare case with catastrophic hemodynamics due to the incidental combination of HOCM and takotsubo syndrome.

• Authors: Yasue Sato, Kensuke Matsumoto, Jun Sakai, Toshihiro Nakamura, Hidekazu Tanaka, Kenichi Hirata
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 59 Issue 7 Pg. 957-962 (Apr 01 2020) ISSN: 1349-7235 [Electronic] Japan
• PMID: 31813917 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adrenergic beta-Antagonists

Topics

• Adrenergic beta-Antagonists (therapeutic use)
• Aged, 80 and over
• Cardiomyopathy, Hypertrophic (complications, physiopathology, therapy)
• Female
• Fluid Therapy (methods)
• Hemodynamics (drug effects)
• Humans
• Takotsubo Cardiomyopathy (etiology, physiopathology, therapy)
• Treatment Outcome