The therapeutic efficacy of high-dose ambroxol and the nursing effects in the treatment of severe pneumonia.

Abstract

To observe and analyze the therapeutic efficacy of high-dose ambroxol in the treatment of severe pneumonia, as well as summarize the nursing methods. A total of 180 patients diagnosed with severe pneumonia and treated at our hospital who were enrolled. The patients were divided into a control group and are search group, with 90 patients in each group. Of those, patients in the research group were treated with high-doses ambroxol, while small-dose ambroxol was administered to patients in the control group. The therapeutic efficacy was compared between both groups. Meanwhile, predictive nursing regimens were applied on patients in the research group, while routine nursing care was given to patients in the control group. The nursing satisfaction was compared between both groups. By comparing the pulmonary function indicators, Comparison of procalcitonin (PCT) and C-reactive protein (CRP) results showed that all indicators of the research group were obviously better than those of the control group (p<0.05). The time of infection control, ICU stay and hospital stay of the research group were significantly less than those of the control group (p<0.05). Moreover, the overall nursing satisfaction of the research group was significantly higher than that of the control group (p<0.05).Application of high-dose ambroxol and scientific nursing methods could significantly improve the therapeutic efficacy in the treatment of severe pneumonia and gain favorable nursing satisfaction.

• Authors: Dongmei Wang, Shu Sun, Songxue Hu
• Journal: Pakistan journal of pharmaceutical sciences (Pak J Pharm Sci) Vol. 32 Issue 3 Special Pg. 1409-1413 (May 2019) ISSN: 1011-601X [Print] Pakistan
• PMID: 31551222 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Expectorants
• Procalcitonin
• Ambroxol
• C-Reactive Protein

Topics

• Administration, Intravenous
• Adult
• Aged
• Ambroxol (administration & dosage, therapeutic use)
• C-Reactive Protein (analysis)
• Dose-Response Relationship, Drug
• Expectorants (administration & dosage, therapeutic use)
• Female
• Humans
• Intensive Care Units
• Lung (diagnostic imaging, drug effects)
• Male
• Middle Aged
• Nursing Care
• Pneumonia (diagnostic imaging, drug therapy)
• Procalcitonin (blood)
• Treatment Outcome
• Young Adult