Abstract | Introduction: The relationship of the metabolic syndrome (MS) and its components with the reduced glomerular filtration rate and proteinuria is not yet widely elucidated. The aim of the study was to associate the estimated glomerular filtration rate (eGFR) and proteinuria to MS and its individual components in adults with cardiometabolic risk factors, who attended a public health center in the municipality of San Diego, Carabobo State, Venezuela. Methods: Results: The frequency of MS was significantly higher among patients with CKD (eGFR < 60 mL/min/m2), mildly reduced eGFR (60-89 mL/min/m2), hyperfiltration or proteinuria. The risks of mildly reduced eGFR and protenuria were significantly associated with elevated fasting blood glucose, low HDLc and MS, with and without adjustment for sex, age and BMI. When adjusted for the diabetic condition, only the risk of proteinuria remained associated with MS and elevated blood pressure. The risk of hyperfiltration was not associated with MS. Conclusion: The reduction in estimated glomerular function and proteinuria were associated with MS and its individual components. Other studies that confirm the results are required.
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Authors | Ulises Leal, Nelina Alejandra Ruiz-Fernández, Lisbeth Loaiza, Milagros Espinoza |
Journal | Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina)
(Rev Fac Cien Med Univ Nac Cordoba)
Vol. 76
Issue 3
Pg. 135-141
(08 29 2019)
ISSN: 1853-0605 [Electronic] Argentina |
Vernacular Title | [Función glomerular y síndrome metabólico en adultos venezolanos con factores de riesgo cardiometabólico atendidos en un centro de atención primaria.] |
PMID | 31465179
(Publication Type: Journal Article)
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Copyright | Universidad Nacional de Córdoba |
Chemical References |
- Cholesterol, HDL
- Cholesterol, LDL
- Triglycerides
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Topics |
- Body Mass Index
- Cardiovascular Diseases
(blood, etiology)
- Cholesterol, HDL
(blood)
- Cholesterol, LDL
(blood)
- Cross-Sectional Studies
- Female
- Glomerular Filtration Rate
- Humans
- Male
- Metabolic Syndrome
(blood, complications)
- Middle Aged
- Primary Health Care
- Risk Factors
- Triglycerides
(blood)
- Venezuela
- Waist Circumference
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