Educational Recommendations on Selected Analytical and Clinical Aspects of Natriuretic Peptides with a Focus on Heart Failure: A Report from the IFCC Committee on Clinical Applications of Cardiac Bio-Markers.

Abstract

The IFCC Committee on Clinical Applications of Cardiac Bio-Markers (C-CB) has directives and initiatives focused on providing evidence-based educational resources to aid and improve understanding around key analytical and clinical aspects of cardiac biomarkers used in clinical practice and the research setting. As a task force, we have previously published position statements and recommendations focused on use and analytical aspects of high-sensitivity cardiac troponin assays. The current educational document is the first from the C-CB highlighting important biochemical, analytical, and clinical aspects as they relate to the natriuretic peptides (NPs), including B-type natriuretic peptide (BNP) and N-terminal pro-B-type natriuretic peptide (NT-proBNP), with a focus on heart failure.

• Authors: Peter A Kavsak, Carolyn S P Lam, Amy K Saenger, Allan S Jaffe, Paul Collinson, Kari Pulkki, Tobjørn Omland, Guillaume Lefèvre, Richard Body, Jordi Ordonez-Llanos, Fred S Apple
• Journal: Clinical chemistry (Clin Chem) Vol. 65 Issue 10 Pg. 1221-1227 (10 2019) ISSN: 1530-8561 [Electronic] England
• PMID: 31387884 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2019 American Association for Clinical Chemistry.

Chemical References

• Biomarkers
• Peptide Fragments
• pro-brain natriuretic peptide (1-76)
• Natriuretic Peptide, Brain

Topics

• Biomarkers (blood)
• Heart Failure (blood)
• Humans
• Immunoassay (methods)
• Natriuretic Peptide, Brain (blood)
• Peptide Fragments (blood)