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Brain Natriuretic Peptide (Natrecor)

A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MYOCARDIUM. It can cause NATRIURESIS; DIURESIS; VASODILATION; and inhibits secretion of RENIN and ALDOSTERONE. It improves heart function. It contains 32 AMINO ACIDS.
Also Known As:
Natrecor; Nesiritide; Peptide, Brain Natriuretic; Natriuretic Peptide, Brain; B-Type Natriuretic Peptide; BNP Gene Product; BNP-32; Brain Natriuretic Peptide-32; Natriuretic Factor-32; Natriuretic Peptide Type-B; Type-B Natriuretic Peptide; Ventricular Natriuretic Peptide, B-type; BNP 32; Brain Natriuretic Peptide 32; Natriuretic Factor 32; Natriuretic Peptide Type B; Natriuretic Peptide, B-Type; Natriuretic Peptide, Type-B; Natriuretic Peptide-32, Brain; Peptide-32, Brain Natriuretic; Type B Natriuretic Peptide; Ventricular Natriuretic Peptide, B type; Natriuretic factor, brain
Networked: 9712 relevant articles (378 outcomes, 1543 trials/studies)

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Drug Context: Research Results

Experts

1. Januzzi, James L: 111 articles (10/2022 - 08/2004)
2. McMurray, John J V: 68 articles (10/2022 - 04/2007)
3. Mueller, Christian: 66 articles (01/2022 - 12/2002)
4. O'Connor, Christopher M: 64 articles (01/2022 - 01/2002)
5. Solomon, Scott D: 63 articles (10/2022 - 05/2008)
6. Hernandez, Adrian F: 62 articles (06/2022 - 12/2007)
7. Omland, Torbjørn: 58 articles (01/2022 - 02/2002)
8. Voors, Adriaan A: 58 articles (11/2021 - 03/2006)
9. Burnett, John C: 58 articles (01/2021 - 02/2002)
10. Maisel, Alan S: 57 articles (12/2021 - 02/2002)

Related Diseases

1. Heart Failure
02/01/2003 - "The results of several recent clinical trials have shown that administration of nesiritide is safe and highly effective for the initial treatment of patients with acutely decompensated heart failure and can help physicians and nurses meet treatment goals for the management of patients with this serious condition."
01/01/2021 - "The results of NMA and SUCRA showed that with conventional treatment (CT) as a common control, in terms of clinical efficacy, CT + XML was most effective in New York Heart Association cardiac functional classification efficiency, brain natriuretic peptide, and N-terminal pro-brain natriuretic peptide; the CT + SM was most effective in 6-min walking test, left ventricular end-diastolic diameter, left ventricular end-systolic diameter and cardiac output; the CT + YQFM was most effective in left ventricular ejection fraction; the CT + HQ was most effective in stroke volume; the CT + SF was most effective in Minnesota Living with Heart Failure Questionnaire. "
11/01/2004 - "Nesiritide has proven to be an effective new treatment for patients with decompensated heart failure."
03/01/2004 - "Nesiritide is a newer neurohormonal agent with proven efficacy and safety for use in decompensated heart failure, but appropriate patient selection has been challenging for clinicians. "
07/09/2021 - "Moreover, EECP was beneficial for left ventricular ejection fraction (SMD = 0.64; 95% CI,0.29 to 1.00; P = .0004), and N-terminal pro brain natriuretic peptide (SMD = -0.61; 95%CI, -1.20 to -0.01; P = 0.04).However, compared with the control groups, EECP did not significantly reduce the Minnesota Living with Heart Failure Questionnaire scores(WMD, -9.28; 95% CI, -19.30 to 0.75; P = 0.07). "
2. Dyspnea (Shortness of Breath)
3. Body Weight (Weight, Body)
4. Left Ventricular Dysfunction
5. Myocardial Infarction

Related Drugs and Biologics

1. pro-brain natriuretic peptide (1-76)
2. Brain Natriuretic Peptide (Natrecor)
3. Biomarkers (Surrogate Marker)
4. Atrial Natriuretic Factor (ANF)
5. C-Reactive Protein
6. Troponin T (Troponin T1)
7. Natriuretic Peptides
8. Troponin
9. Messenger RNA (mRNA)
10. Troponin I

Related Therapies and Procedures

1. Therapeutics
2. Critical Care (Surgical Intensive Care)
3. Percutaneous Coronary Intervention
4. Cardiac Resynchronization Therapy
5. Patient Readmission