Abstract | BACKGROUND: METHODS: One hundred adult participants were enrolled in this study conducted in Chengdu, China. After random assignment and blinding of examiners and patients, enrolled participants received instructions for use of the assigned dentifrice. At 3 visits (baseline and 3 and 6 months), the authors measured various gingival and plaque indexes to determine the clinical efficacy of the stabilized SnF2 dentifrice compared with those of the control fluoride dentifrice (2 groups). RESULTS: Ninety-eight participants completed the study. Both groups (test and control) had statistically significant reductions in gingival inflammation and improvement in plaque control at the 3- and 6-month follow-ups. In addition, the test dentifrice showed statistically significant reductions in all indexes compared with the control dentifrice (P < .001). CONCLUSIONS: This study's results show statistically significantly improved clinical outcomes for reduction of gingival inflammation and improvement in biofilm control over a 6-month period through the use of a SnF2 dentifrice stabilized with zinc phosphate when compared with results with a fluoride control dentifrice. PRACTICAL IMPLICATIONS: This newly formulated dentifrice improves gingival health and plaque control and thereby may aid patients in attaining improved oral health.
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Authors | Deyu Hu, Xue Li, Hongchun Liu, Luis R Mateo, Amarpreet Sabharwal, Guofeng Xu, Gregory Szewczyk, Maria Ryan, Yun-Po Zhang |
Journal | Journal of the American Dental Association (1939)
(J Am Dent Assoc)
Vol. 150
Issue 4S
Pg. S32-S37
(04 2019)
ISSN: 1943-4723 [Electronic] England |
PMID | 30797257
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2019 American Dental Association. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Dentifrices
- Tin Fluorides
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Topics |
- Adult
- Analysis of Variance
- Dental Plaque
- Dental Plaque Index
- Dentifrices
- Double-Blind Method
- Follow-Up Studies
- Gingivitis
- Humans
- Periodontal Index
- Tin Fluorides
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