Abstract | RATIONALE: Considering the low incidence of colorectal follicular lymphoma (FL) and its clinical features in endoscopic views, only a few studies have described the pathological diagnosis and treatment of this disease. This study aimed to reveal the overall process of clinical diagnosis and treatment of colorectal FL by conducting a case review. PATIENT CONCERNS: A 27-year-old female presented to our department because of "severe bloody stool" lasting for more than 1 month. Her primary symptom was melena. Colonoscopy revealed widespread flat polyps with various immunophenotypes (CD10+, BCL2+, BCL6+, cyclin D1-, CD5-) in the colorectal area. DIAGNOSIS: In accordance with manifestations on positron emission tomography-computed tomography (PET/CT), the patient was diagnosed with stage IV colorectal FL. INTERVENTIONS: OUTCOMES: Lesions on PET/CT disappeared after reexamination. No recurrence was observed within the 12-month follow-up period. LESSONS: Colorectal FL is a rare disease with an inert clinical course and is common in the ileocecal area. Endoscopic views show multiple polyps. Interventional treatment is usually provided after observation of clinical symptoms or during disease progression. The disease has a relatively good prognosis.
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Authors | Mei-Lian Wang, Jiang Chang, Hua Huang, Wen Fu, Yi-Chun Niu, Ming-Liang Lu, Shikha Shrestha |
Journal | Medicine
(Medicine (Baltimore))
Vol. 98
Issue 3
Pg. e13985
(Jan 2019)
ISSN: 1536-5964 [Electronic] United States |
PMID | 30653103
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antineoplastic Agents, Immunological
- Rituximab
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Topics |
- Adult
- Aftercare
- Antineoplastic Agents, Immunological
(administration & dosage, therapeutic use)
- Antineoplastic Combined Chemotherapy Protocols
(administration & dosage, therapeutic use)
- Colonoscopy
(methods)
- Colorectal Neoplasms
(diagnostic imaging, metabolism, pathology)
- Female
- Humans
- Lymphoma, Follicular
(drug therapy, metabolism, pathology)
- Melena
(diagnosis, etiology)
- Neoplasm Staging
- Positron Emission Tomography Computed Tomography
(methods)
- Rare Diseases
- Rituximab
(administration & dosage, therapeutic use)
- Treatment Outcome
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