[Primary Pulmonary Synovial Sarcoma;Report of a Case].

Abstract

A 66-year-old man was referred to our hospital for an abnormal shadow. Chest computed tomography (CT)showed a heterogeneous mass with well-defined border in the right S10and ipsilateral pleural effusion. Fluorodeoxyglucose-positron emission tomography(FDG-PET)showed the accumulation in the mass and pleural effusion. Right lower lobectomy with lymphnode dissection was performed for diagnosis and treatment. Histologically,the tumor was mainly composed of complicated spindle-shaped cells with extensive necrosis, showing a large number of nuclear fission images. Immunohistochemistry showed the tumor cells to be positive for cytokeratin AE1/AE3, Bcl-2, EMA, vimentin and negative for TTF-1, S-100, calretinin, CD34, being compatible with monophasic fibrous synovial sarcoma.

• Authors: Toshio Nishikawa, Masahiko Takahashi, Masanobu Mori, Takahiro Okabayashi, Yasuaki Kamikawa, Fumiyuki Inoue
• Journal: Kyobu geka. The Japanese journal of thoracic surgery (Kyobu Geka) Vol. 71 Issue 8 Pg. 637-639 (Aug 2018) ISSN: 0021-5252 [Print] Japan
• PMID: 30185765 (Publication Type: Case Reports)

Chemical References

• Neoplasm Proteins

Topics

• Aged
• Humans
• Immunohistochemistry
• Lung Neoplasms (chemistry, diagnostic imaging, surgery)
• Male
• Neoplasm Proteins (analysis)
• Pleural Effusion (diagnostic imaging)
• Positron Emission Tomography Computed Tomography
• Sarcoma, Synovial (chemistry, diagnostic imaging, surgery)
• Tomography, X-Ray Computed