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Synovial Sarcoma (Synovioma)

A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363)
Also Known As:
Synovioma; Sarcoma, Synovial; Sarcomas, Synovial; Synovial Sarcomas; Synoviomas
Networked: 1230 relevant articles (79 outcomes, 190 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Sarcoma (Soft Tissue Sarcoma)
3. Liposarcoma
4. Ewing Sarcoma (Sarcoma, Ewing)
5. Neoplasm Metastasis (Metastasis)

Experts

1. Kawai, Akira: 23 articles (07/2022 - 04/2002)
2. Nielsen, Torsten O: 21 articles (01/2022 - 10/2003)
3. Oda, Yoshinao: 15 articles (01/2022 - 04/2002)
4. Iwamoto, Yukihide: 13 articles (01/2022 - 04/2002)
5. Araki, Nobuhito: 13 articles (08/2019 - 08/2002)
6. Ladanyi, Marc: 13 articles (12/2018 - 02/2002)
7. Toguchida, Junya: 13 articles (01/2015 - 10/2002)
8. Jones, Robin L: 12 articles (01/2022 - 05/2011)
9. Wang, Jian: 12 articles (05/2021 - 07/2002)
10. Yamamoto, Hidetaka: 11 articles (01/2022 - 05/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Synovial Sarcoma:
1. Doxorubicin (Adriamycin)FDA LinkGeneric
2. IfosfamideFDA LinkGeneric
3. AntigensIBA
4. Proteins (Proteins, Gene)FDA Link
5. pazopanibFDA Link
6. Biomarkers (Surrogate Marker)IBA
7. AntibodiesIBA
8. T-Cell Antigen Receptors (T-Cell Receptor)IBA
9. TrabectedinIBA
10. eribulinFDA Link

Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Radiotherapy
4. Immunotherapy
5. Neoadjuvant Therapy