Abstract | OBJECTIVES: METHODS: In this double-masked clinical study, 60 patients treated bilaterally with PRK were randomly allocated into two groups. Postoperatively, one group of patients received diclofenac 0.1% drops and the other group was prescribed ketorolac 0.5% ophthalmic drops in both eyes every 6 hr on the first day and then, no NSAID was applied until the third day. No oral analgesic drug was used after surgery. Patients completed the Visual Analog Scale questionnaire to determine the degree of pain and ocular discomfort (tearing, foreign body sensation, blurred vision, and photophobia) on the first and the third day after surgery. RESULTS:
Pain relief was achieved with both medications after surgery, and there was no significant intergroup difference in the level of pain reduction at 24 and 72 hr postoperatively (P>0.05). The ketorolac group experienced less tearing and photophobia only at 24 hr postoperatively (P=0.01), and by 72 hr after surgery, the results were similar in two groups (P>0.05). There was no significant intergroup difference in terms of foreign body sensation or blurred vision on the first or third postoperative days (P>0.05). CONCLUSIONS:
|
Authors | Mehrdad Mohammadpour, Zahra Heidari, Ratishta Molani |
Journal | Eye & contact lens
(Eye Contact Lens)
Vol. 45
Issue 2
Pg. 137-140
(Mar 2019)
ISSN: 1542-233X [Electronic] United States |
PMID | 29944510
(Publication Type: Journal Article, Randomized Controlled Trial)
|
Chemical References |
- Anti-Inflammatory Agents, Non-Steroidal
- Ophthalmic Solutions
- Diclofenac
- Ketorolac
|
Topics |
- Adult
- Anti-Inflammatory Agents, Non-Steroidal
(administration & dosage)
- Diclofenac
(administration & dosage)
- Double-Blind Method
- Female
- Humans
- Ketorolac
(administration & dosage)
- Lasers, Excimer
(therapeutic use)
- Male
- Myopia
(surgery)
- Ophthalmic Solutions
- Pain Management
(methods)
- Pain Measurement
- Pain, Postoperative
(diagnosis, drug therapy)
- Photorefractive Keratectomy
(adverse effects)
- Treatment Outcome
- Visual Acuity
- Young Adult
|