Abstract | BACKGROUND: Pre-pectoral breast reconstruction is an emerging surgical approach. This study provides an early assessment of outcomes with the technique. METHODS: A comprehensive literature review was performed through searches of PubMed® /MEDLINE® to identify studies on pre-pectoral reconstruction. Patient characteristics and outcomes were extracted from studies and pooled. Linear relationships between complication rates and patient characteristics with pre-pectoral reconstruction were analyzed. A meta-analysis compared complication rates between pre-pectoral and dual-plane reconstruction. RESULTS: Fourteen studies (406 women/654 breasts) were included. The most common complications with pre-pectoral reconstruction were flap necrosis (7.8%), seroma (6.7%), capsular contracture (5.8%), and explantation (4.6%). No hyperanimation was reported. Significant correlation between previous radiation and flap necrosis, post-operative chemotherapy and infection, hypertension and flap necrosis, diabetes and dehiscence, and smoking and explantation were found. A meta-analysis of four studies comparing pre-pectoral (135 women/219 breasts) and dual-plane (230/408) reconstruction found no significant difference for likelihood of infection (odds ratio, 0.46; 95% confidence interval, 0.16-1.30), explantation (0.83; 0.29-2.38), necrosis (1.61; 0.77-3.36), seroma (1.88; 0.71-5.02), dehiscence (1.84; 0.68-4.95), or capsular contracture (0.14; 0.02-1.14). CONCLUSIONS: Complication rates are comparable following pre-pectoral and dual-plane reconstruction, indicating the pre-pectoral technique may be a feasible option for appropriate patients.
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Authors | Abhishek Chatterjee, Maurice Y Nahabedian, Allen Gabriel, David Macarios, Mousam Parekh, Fang Wang, Leah Griffin, Steven Sigalove |
Journal | Journal of surgical oncology
(J Surg Oncol)
Vol. 117
Issue 6
Pg. 1119-1130
(May 2018)
ISSN: 1096-9098 [Electronic] United States |
PMID | 29346711
(Publication Type: Journal Article, Meta-Analysis, Review)
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Copyright | © 2018 Wiley Periodicals, Inc. |
Topics |
- Breast Neoplasms
(surgery)
- Female
- Humans
- Mammaplasty
(adverse effects)
- Postoperative Complications
- Prognosis
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