Abstract | BACKGROUND: METHODS: RESULTS: A total of 101 patients were included with a median follow-up of 42 months. In total, 55% were male, and the median age was 58 years (29-87 years). Fifty-one (50.5%) patients developed oligoclonal bands. They comprised 60% (45/75) of patients treated with autologous stem cell transplantation and 23% (6/26) of those who were not transplanted. Patients with oligoclonal bands showed better progression-free survival than those without the emergence of oligoclonal bands (p-value=0.0075). CONCLUSION: The prevalence of oligoclonal bands in this study population was 50.5% with its frequency being greater in cases treated with autologous stem cell transplantation and in those attaining complete remission. Complete remission was more important than the emergence of oligoclonal bands on progression-free survival.
|
Authors | Luiza Soares Vieira da Silva, Edvan de Queiroz Crusoe, Lais Rocha Guimarães de Souza, Carlos Sérgio Chiattone, Vânia Tietsche de Moraes Hungria |
Journal | Revista brasileira de hematologia e hemoterapia
(Rev Bras Hematol Hemoter)
2017 Oct - Dec
Vol. 39
Issue 4
Pg. 331-336
ISSN: 1516-8484 [Print] Brazil |
PMID | 29150105
(Publication Type: Journal Article)
|
Copyright | Copyright © 2017. Published by Elsevier Editora Ltda. |