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Multiple Myeloma

A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
Also Known As:
Kahler Disease; Myeloma, Multiple; Myeloma-Multiple; Myelomatosis; Plasma Cell Myeloma; Cell Myeloma, Plasma; Cell Myelomas, Plasma; Disease, Kahler; Multiple Myelomas; Myeloma Multiple; Myeloma, Plasma Cell; Myeloma-Multiples; Myelomas, Multiple; Myelomas, Plasma Cell; Myelomas, Plasma-Cell; Myelomatoses; Plasma Cell Myelomas; Plasma-Cell Myeloma; Plasma-Cell Myelomas; Myeloma, Plasma-Cell
Networked: 26492 relevant articles (2317 outcomes, 4116 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Lymphoma (Lymphomas)
3. Non-Hodgkin Lymphoma (Lymphosarcoma)
4. Hematologic Neoplasms (Hematological Malignancy)
5. Breast Neoplasms (Breast Cancer)

Experts

1. Anderson, Kenneth C: 512 articles (06/2022 - 01/2002)
2. Richardson, Paul G: 329 articles (10/2022 - 06/2002)
3. Moreau, Philippe: 279 articles (10/2022 - 01/2002)
4. Dimopoulos, Meletios A: 237 articles (12/2022 - 10/2003)
5. Goldschmidt, Hartmut: 229 articles (10/2022 - 09/2002)
6. Hideshima, Teru: 219 articles (06/2022 - 01/2002)
7. Palumbo, Antonio: 211 articles (09/2021 - 06/2002)
8. Rajkumar, S Vincent: 197 articles (10/2022 - 02/2002)
9. Lonial, Sagar: 197 articles (06/2022 - 01/2003)
10. Munshi, Nikhil C: 188 articles (06/2022 - 02/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Multiple Myeloma:
1. Bortezomib (Velcade)FDA Link
2. Dexamethasone (Maxidex)FDA LinkGeneric
3. Lenalidomide (CC 5013)FDA Link
4. Thalidomide (Thalomid)FDA Link
5. Proteasome InhibitorsIBA
6. Melphalan (Alkeran)FDA LinkGeneric
7. Immunomodulating AgentsIBA
8. daratumumabIBA
9. carfilzomibIBA
10. Cyclophosphamide (Cytoxan)FDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Stem Cell Transplantation
4. Transplantation
5. Hematopoietic Stem Cell Transplantation