Neurosarcoidosis.

Abstract

Neurosarcoidosis occurs in 3% to 10% of patients with sarcoidosis. Cranial neuropathy and meningeal involvement are the most common manifestations, but any part of the nervous system can be affected. Definite diagnosis requires the presence of noncaseating granuloma in the nervous system, although histopathologic confirmation is often not obtainable. Moderate to high dose of glucocorticoids is the main therapy for neurosarcoidosis. Relapse often occurs after the dose of glucocorticoids is tapered down, often necessitating the use of steroid-sparing immunosuppressive agents.

• Authors: Patompong Ungprasert, Eric L Matteson
• Journal: Rheumatic diseases clinics of North America (Rheum Dis Clin North Am) Vol. 43 Issue 4 Pg. 593-606 (11 2017) ISSN: 1558-3163 [Electronic] United States
• PMID: 29061245 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2017 Elsevier Inc. All rights reserved.

Topics

• Central Nervous System Diseases (diagnosis, etiology, therapy)
• Humans
• Sarcoidosis (diagnosis, etiology, therapy)