Prophylactic role of taurine and its derivatives against diabetes mellitus and its related complications.

Abstract

Taurine is a conditionally essential amino acid present in the body in free form. Mammalian taurine is synthesized in the pancreas via the cysteine sulfinic acid pathway. Anti-oxidation and anti-inflammation are two main properties through which it exerts its therapeutic effects. Many studies have shown its excellent therapeutic potential against diabetes mellitus and related complications like diabetic neuropathy, retinopathy, nephropathy, hematological dysfunctions, reproductive dysfunctions, liver and pancreas related complications etc. Not only taurine, a number of its derivatives have also been reported to be important in ameliorating diabetic complications. The present review has been aimed to describe the importance of taurine and its derivatives against diabetic metabolic syndrome and related complications.

• Authors: Poulami Sarkar, Priyanka Basak, Sumit Ghosh, Mousumi Kundu, Parames C Sil
• Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association (Food Chem Toxicol) Vol. 110 Pg. 109-121 (Dec 2017) ISSN: 1873-6351 [Electronic] England
• PMID: 29050977 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2017 Elsevier Ltd. All rights reserved.

Chemical References

• Blood Glucose
• Taurine

Topics

• Animals
• Blood Glucose (metabolism)
• Diabetes Complications (metabolism, prevention & control)
• Diabetes Mellitus, Type 2 (complications, metabolism)
• Humans
• Oxidative Stress (drug effects)
• Taurine (administration & dosage)