Fatal invasive aspergillosis caused by Aspergillus niger after bilateral lung transplantation.

Abstract

Aspergillus niger is usually considered to be a low virulence fungus, not commonly reported to cause invasive infections. Invasive pulmonary aspergillosis due to Aspergillus niger was diagnosed in a 43-year-old woman following bilateral lung transplantation. Intravenous voriconazole failed to control progression of the disease. Despite salvage therapy with a combination of voriconazole and caspofungin for 23 days, the patient developed massive hemoptysis leading to death. The authors report the clinical features and treatment of this case.

• Authors: Enora Atchade, Sylvain Jean-Baptiste, Sandrine Houzé, Claire Chabut, Laurent Massias, Yves Castier, Olivier Brugière, Hervé Mal, Philippe Montravers
• Journal: Medical mycology case reports (Med Mycol Case Rep) Vol. 17 Pg. 4-7 (Sep 2017) ISSN: 2211-7539 [Print] Netherlands
• PMID: 28560131 (Publication Type: Journal Article)