Abstract | PURPOSE: METHODS: We selected 680 women with singleton pregnancy and cardiovascular events at labor/delivery from 12 U.S. clinical sites (2002-2008). Exposures to six criteria air pollutants, six particulate constituents, and 26 air toxics were obtained using modified Community Multiscale Air Quality models. Conditional logistic regression models calculated the odds ratio (OR) and 95% confidence intervals (CI) comparing exposures during the day of delivery, the week before delivery, and each of the days of the week before delivery to two control periods before and after. RESULTS: An interquartile range increase in particulate matter (PM) ≤2.5 microns and nitric oxide exposures during the week before delivery was associated with an 11% (OR 1.11, 95% CI: 1.01-1.23) and 21% (OR 1.21, 95% CI: 1.04-1.42) increased cardiovascular events odds, respectively. These pollutants, sulfur dioxide, carbon monoxide, PM ≤ 10 microns, and some PM constituents showed associations with event odds for days 0, 1, 5, and 6 before delivery. Inverse associations were observed for O3 and some PM constituents as well as air toxics. CONCLUSIONS: Cardiovascular events at labor/delivery merit more attention in relation to air pollution.
|
Authors | Sandie Ha, Tuija Männistö, Danping Liu, Seth Sherman, Qi Ying, Pauline Mendola |
Journal | Annals of epidemiology
(Ann Epidemiol)
Vol. 27
Issue 6
Pg. 377-383
(06 2017)
ISSN: 1873-2585 [Electronic] United States |
PMID | 28552468
(Publication Type: Journal Article, Research Support, N.I.H., Intramural)
|
Copyright | Published by Elsevier Inc. |
Chemical References |
- Air Pollutants
- Particulate Matter
- Sulfur Dioxide
- Nitric Oxide
- Carbon Monoxide
|
Topics |
- Adult
- Air Pollutants
(adverse effects, analysis)
- Air Pollution
(adverse effects, analysis)
- Carbon Monoxide
(administration & dosage, adverse effects)
- Cardiovascular Diseases
(epidemiology, etiology)
- Cross-Over Studies
- Delivery, Obstetric
- Environmental Exposure
- Female
- Heart Arrest
(epidemiology, etiology)
- Heart Failure
(epidemiology, etiology)
- Humans
- Labor, Obstetric
- Nitric Oxide
(administration & dosage, adverse effects)
- Particulate Matter
(adverse effects, analysis)
- Parturition
- Pregnancy
- Stroke
(epidemiology, etiology)
- Sulfur Dioxide
(administration & dosage, adverse effects)
|