Catechins and Its Role in Chronic Diseases.

Abstract

The mechanisms of action of polyphenols have attracted much attention. Catechins are generally known as tea polyphenols. Researchers have extensively investigated the molecular mechanisms of these substances, especially (-)-epigallocatechin gallate of green tea catechin, and have provided new insights in the prevention and therapy for chronic diseases. This chapter summarizes catechins and their effects on chronic diseases, including metabolic syndromes, cardiovascular diseases, neurodegenerative diseases, and cancer, focusing on the effects of green tea catechins.

• Authors: Yohei Shirakami, Hiroyasu Sakai, Takahiro Kochi, Mitsuru Seishima, Masahito Shimizu
• Journal: Advances in experimental medicine and biology (Adv Exp Med Biol) Vol. 929 Pg. 67-90 ( 2016) ISSN: 0065-2598 [Print] United States
• PMID: 27771921 (Publication Type: Journal Article, Review)

Chemical References

• Antineoplastic Agents, Phytogenic
• Cardiovascular Agents
• Neuroprotective Agents
• Plant Extracts
• Tea
• Catechin

Topics

• Animals
• Antineoplastic Agents, Phytogenic (chemistry, isolation & purification, therapeutic use)
• Cardiovascular Agents (chemistry, isolation & purification, therapeutic use)
• Catechin (chemistry, isolation & purification, therapeutic use)
• Chronic Disease (drug therapy)
• Disease Models, Animal
• Drug Discovery (methods)
• Humans
• Molecular Structure
• Neuroprotective Agents (chemistry, isolation & purification, therapeutic use)
• Phytotherapy
• Plant Extracts (chemistry, isolation & purification, therapeutic use)
• Plants, Medicinal
• Signal Transduction (drug effects)
• Structure-Activity Relationship
• Tea (chemistry)