Clinical features of 10 cases of eyelid sporotrichosis in Jilin Province (Northeast China).

Abstract

OBJECTIVE:

Sporotrichosis is a common subcutaneous mycosis caused by an infection with dimorphic fungus Sporothrix schenckii. We present a series of patients with eyelid sporotrichosis and study the clinical and histopathological presentation, microbiology, treatment options, and outcome.

METHODS:

A retrospective case-series study of patients with a clinical diagnosis of eyelid sporotrichosis. Records were examined to obtain information regarding patient demographics, presenting symptoms and signs, histopathological examination, microbiology, management, and outcomes.

RESULTS:

Ten patients (4 men, 6 women; mean age 46.5 years, range 3-81 years) were included. Based on their clinical manifestations, eyelid sporotrichosis was classified into 3 major forms: (i) fixed cutaneous (6/10 cases), (ii) lymphocutaneous (3/10 cases), and (iii) eyelid abscess (1/10 cases). All the cases were treated with a terbinafine 12-week regimen. Nodules, papules, and abscesses regressed after treatment. No recurrence was discovered after a 12-week follow-up.

CONCLUSIONS:

Eyelid sporotrichosis has typical features of clinical manifestations. Histopathological examination and tissue culture are helpful for diagnosis. Confirmed cases normally require long-term systematic treatment with antifungal agents, but surgical removal is normally unnecessary.

• Authors: Bin Fan, Jin-Feng Wang, Bin Zheng, Xin-Zhu Qi, Jing-Yao Song, Guang-Yu Li
• Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie (Can J Ophthalmol) Vol. 51 Issue 4 Pg. 297-301 (Aug 2016) ISSN: 1715-3360 [Electronic] England
• PMID: 27521671 (Publication Type: Journal Article)
• Copyright: Copyright © 2016 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

Chemical References

• Antifungal Agents
• Naphthalenes
• Terbinafine

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Antifungal Agents (therapeutic use)
• Child
• Child, Preschool
• China
• Eye Infections, Fungal (diagnosis, drug therapy, microbiology)
• Eyelid Diseases (diagnosis, drug therapy, microbiology)
• Female
• Humans
• Male
• Middle Aged
• Naphthalenes (therapeutic use)
• Retrospective Studies
• Sporothrix (isolation & purification)
• Sporotrichosis (diagnosis, drug therapy, microbiology)
• Terbinafine