Recovery with a regular dose of antibiotics from bacillary hemoglobinuria in a Holstein cow.

Abstract

One Holstein cow housed with 21 other cows exhibited clinical signs of pyrexia, anorexia and diarrhea along with severe hemoglobinuria. Hematological and biochemical analyses conducted before and after antibiotic therapy indicated severe hemolytic anemia and disruption of hepatic function. A general improvement in conditions was observed after an 11-day program of treatment comprising a regular dose of antibiotics and prescribed supportive therapies. A tentative diagnosis of bacillary hemoglobinuria was made based on the clinical and clinico-pathologic features on day 7. A molecular diagnosis was made by a PCR amplification of the flagellin gene of Clostridium haemolyticum using DNA extracted from the whole blood. The cow was diagnosed with the first recorded occurrence of bacillary hemoglobinuria of Holstein cattle in Japan.

• Authors: Mitsuhiro Takagi, Moeko Kohyama, Tetsushi Ono, Satoshi Adachi, Daiji Shirao, Hidenori Tamura, Masayasu Taniguchi, Akira Yabuki, Osamu Yamato
• Journal: The Journal of veterinary medical science (J Vet Med Sci) Vol. 78 Issue 11 Pg. 1737-1740 (Dec 01 2016) ISSN: 1347-7439 [Electronic] Japan
• PMID: 27498996 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Bacterial Agents

Topics

• Anemia, Hemolytic (microbiology, veterinary)
• Animals
• Anti-Bacterial Agents (therapeutic use)
• Cattle
• Cattle Diseases (drug therapy, microbiology, urine)
• Clostridium (isolation & purification)
• Clostridium Infections (drug therapy, microbiology, urine, veterinary)
• Female
• Hemoglobinuria (drug therapy, microbiology, veterinary)
• Japan