Abstract |
We previously observed increased odds of ST-elevation myocardial infarctions (STEMIs) associated with increased ambient fine particulate matter (PM2.5) in the previous hour. However, data are lacking on the effects of specific PM sources. Using data from 362 patients, a case-crossover design, and conditional logistic regression, we estimated the relative odds of STEMI associated with increased Delta-C (wood smoke), black carbon (BC; traffic), PM2.5, and gaseous pollutants in the previous 1-72 h. We did not observe increased odds of STEMIs associated with increased Delta-C or BC. We did observe increased odds associated with each 7.1 μg/m3 increase in PM2.5 (OR (95% CI): 1.17 (0.99, 1.39)) and each 19.9 p.p.b. increase in ozone (O3; 1.27 (1.00, 1.63)) in the previous hour, and each 0.22 p.p.m. increase in 48-h carbon monoxide (CO) concentrations (1.32 (1.00, 1.73]). Larger relative odds were associated with PM2.5 in May-October, and O3 and CO in November-April. Increased PM2.5, O3, and CO, but not wood smoke or BC, were associated with increased odds of STEMI, and effects may differ by season. Studies using spatially adjusted pollution estimates are needed, as well as studies further examining O3 and CO effects on the risk of STEMI.
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Authors | Kristin A Evans, Philip K Hopke, Mark J Utell, Cathleen Kane, Sally W Thurston, Frederick S Ling, David Chalupa, David Q Rich |
Journal | Journal of exposure science & environmental epidemiology
(J Expo Sci Environ Epidemiol)
Vol. 27
Issue 2
Pg. 198-206
(03 2017)
ISSN: 1559-064X [Electronic] United States |
PMID | 27072425
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Chemical References |
- Air Pollutants
- Particulate Matter
- Smoke
- Vehicle Emissions
- Ozone
- Carbon Monoxide
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Topics |
- Adult
- Aged
- Air Pollutants
(adverse effects, analysis)
- Air Pollution
(adverse effects, analysis)
- Carbon Monoxide
(adverse effects, analysis)
- Cross-Over Studies
- Databases, Factual
- Electrocardiography
- Environmental Monitoring
- Female
- Hospitals, University
- Humans
- Logistic Models
- Male
- Middle Aged
- Myocardial Infarction
(chemically induced)
- New York
- Ozone
(adverse effects, analysis)
- Particulate Matter
(adverse effects)
- Seasons
- Smoke
(adverse effects)
- Vehicle Emissions
- Wood
(adverse effects)
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