Liver cancer, with a very high prevalence, is one of the most common causes of death worldwide. Galectin-9, a semi-galactoside-
binding protein, was demonstrated to be involved in the formation and
metastasis processes of
tumors such as
breast cancer, and has significant impact on the development and prognosis of
tumor. In this study, 90 cases of
liver cancer patients who had
liver cancer resection surgery treatment, were selected. Samples of
liver cancer tissues and
cancer-adjacent tissues from the surgery resection of
liver cancer patients, which also confirmed by pathology after operation as specimens, were obtained to detect the expression level of Galectin-9
mRNA. The comparing results showed that there were significant differences between the expression of Galectin-9
mRNA in
cancer-adjacent tissues and that in
cancer tissues (P < 0.05), in terms of pathology differentiation, TNM, and recurrence transfer aspects. However, there were no obvious correlations with gender, age, the size of
tumor, and
HBsAg. The expression of Galectin-9
mRNA has a close relationship with pathological differentiation, TNM, and recurrence
metastasis. Our data presented here provide theoretical basis for new target of
liver cancer diagnosis as well as potential prognosis.