[A Case of Pure Type Mucinous Carcinoma Recurrence after Local Control].

Abstract

The patient was a 44-year-old woman. Mastectomy and sentinel lymph node biopsy had been performed for carcinoma of the left breast approximately 1 year previously. The diagnosis was mucinous carcinoma, T3N0M0, stage ⅡB, ER(+), PgR(+), HER2 score 0, Ki-67 20%. Hormone therapy was administered postoperatively. Four months after the surgery, left axilla lymphadenopathy was observed. Chemotherapy with EC and nab-PTX was started for the postoperative lymph node recurrence. To achieve local control, axillary lymphadenectomy was performed within 1 year postoperatively, and 1 metastatic lesion in the lymph nodes was observed. Hormone therapy was started sequentially, with no subsequent recurrence or metastasis. Mucinous carcinomas are classified as a breast cancer subtype. Mixed type, including breast ductal carcinoma, form a large proportion of mucinous carcinomas and the therapy for breast ductal carcinoma is usually administered in such cases. Conversely, pure type mucinous carcinomas rarely show metastasis and have a good prognosis. In this case, however, metastasis was noted and chemotherapy was not completely effective, and local control was achieved with surgical resection.

• Authors: Katsuhisa Enomoto, Kenichi Sakurai, Sadao Amano
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 42 Issue 12 Pg. 1632-4 (Nov 2015) ISSN: 0385-0684 [Print] Japan
• PMID: 26805120 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Tamoxifen
• Gonadotropin-Releasing Hormone

Topics

• Adenocarcinoma, Mucinous (drug therapy, secondary, surgery)
• Adult
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Axilla
• Breast Neoplasms (drug therapy, pathology, surgery)
• Female
• Gonadotropin-Releasing Hormone (antagonists & inhibitors)
• Humans
• Lymph Node Excision
• Lymph Nodes (pathology)
• Lymphatic Metastasis
• Mastectomy
• Recurrence
• Sentinel Lymph Node Biopsy
• Tamoxifen (administration & dosage)