Abstract |
We report the first case of spondylitis with bacteremia caused by Campylobacter fetus subsp. testudinum identified by 16S ribosomal ribonucleic acid (rRNA) gene sequencing. An 81-year-old man presented with fever and general weakness. His medical history included end-stage renal disease, hypertension, and type 2 diabetes. Despite empirical antibiotic treatment, his fever and back pain persisted. Magnetic resonance imaging with gadolinium enhancement showed a low-signal-intensity lesion in T1-weighted imaging and a high-signal-intensity lesion in T2-weighted imaging at the L3 vertebral body. C. fetus grew on 1 pair of blood cultures. C. fetus subsp. testudinum was identified via 16S rRNA sequencing of the cultivated organisms. The patient recovered uneventfully after 6 weeks of optimal antibiotic treatment, selected using susceptibility tests. C. fetus spondylitis is a very rare disease. In this unique case involving end-stage renal disease, the underlying pathogen was identified by 16S rRNA sequencing.
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Authors | Hong Sang Choi, Sung Un Shin, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim |
Journal | Japanese journal of infectious diseases
(Jpn J Infect Dis)
Vol. 69
Issue 6
Pg. 517-519
(Nov 22 2016)
ISSN: 1884-2836 [Electronic] Japan |
PMID | 26743148
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- DNA, Ribosomal
- RNA, Ribosomal, 16S
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Topics |
- Aged, 80 and over
- Anti-Bacterial Agents
(therapeutic use)
- Bacteremia
(diagnosis, drug therapy, etiology, pathology)
- Bacteriological Techniques
- Campylobacter Infections
(diagnosis, drug therapy, microbiology, pathology)
- Campylobacter fetus
(classification, genetics, isolation & purification)
- DNA, Ribosomal
(chemistry, genetics)
- Humans
- Lumbar Vertebrae
(diagnostic imaging)
- Magnetic Resonance Imaging
- Male
- RNA, Ribosomal, 16S
(genetics)
- Renal Insufficiency, Chronic
(complications)
- Sequence Analysis, DNA
- Spondylitis
(diagnosis, drug therapy, etiology, pathology)
- Treatment Outcome
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