Intravenous Artesunate Reduces Parasite Clearance Time, Duration of Intensive Care, and Hospital Treatment in Patients With Severe Malaria in Europe: The TropNet Severe Malaria Study.
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| Abstract |
Intravenous artesunate improves survival in severe malaria, but clinical trial data from nonendemic countries are scarce. The TropNet severe malaria database was analyzed to compare outcomes of artesunate vs quinine treatment. Artesunate reduced parasite clearance time and duration of intensive care unit and hospital treatment in European patients with imported severe malaria.
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| Authors | Florian Kurth, Michel Develoux, Matthieu Mechain, Jan Clerinx, Spinello Antinori, Ida E Gjørup, Joaquím Gascon, Kristine Mørch, Emanuele Nicastri, Michael Ramharter, Alessandro Bartoloni, Leo Visser, Thierry Rolling, Philipp Zanger, Guido Calleri, Joaquín Salas-Coronas, Henrik Nielsen, Gudrun Just-Nübling, Andreas Neumayr, Anna Hachfeld, Matthias L Schmid, Pietro Antonini, Peter Pongratz, Peter Kern, José Saraiva da Cunha, Antoni Soriano-Arandes, Mirjam Schunk, Norbert Suttorp, Christoph Hatz, Thomas Zoller, TropNet Severe Malaria Investigator Group |
| Journal | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (Clin Infect Dis) Vol. 61 Issue 9 Pg. 1441-4 (Nov 01 2015) ISSN: 1537-6591 [Electronic] United States |
| PMID | 26187021 (Publication Type: Journal Article, Multicenter Study, Observational Study, Research Support, Non-U.S. Gov't) |
| Copyright | © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: [email protected]. |
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