Case report of fatal Mycobacterium tilburgii infection.

Abstract

There are few reports concerning Mycobacterium tilburgii infection in humans because this bacterium is non-cultivatable. Herein, using new molecular techniques, we report the case of an immunocompromised patient with fatal disseminated lymphadenitis that was caused by M. tilburgii.26 years old Caucasian HIV negative female patient presented with abdominal pain. Her clinical assessment revealed disseminated lymphadenitis, that was acid fast bacilli positive. Further molecular evaluation showed the causative agent as M. tilburgii. Despite anti mycobacterial therapy and careful management of intervening complications patient died because of an intraabdominal sepsis. This is the first fatal M. tilburgii infection in the literature. This case points the importance of careful management of patient's immune status and intervening infections besides implementation of effective drug treatment.

• Authors: Timur Akpinar, Oguz K Bakkaloglu, Burak Ince, Fatih Tufan, Murat Kose, Mehves Poda, Didem Tascioglu, O Kaya Koksalan, Bulent Saka, Nilgun Erten, Nesimi Buyukbabani, Zeki Kilicaslan, Cemil Tascioglu
• Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (J Infect Chemother) Vol. 21 Issue 7 Pg. 538-40 (Jul 2015) ISSN: 1437-7780 [Electronic] Netherlands
• PMID: 25818194 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2015 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Topics

• Adult
• Fatal Outcome
• Female
• Humans
• Lymph Nodes (microbiology, pathology)
• Lymphadenitis
• Molecular Sequence Data
• Mycobacterium (genetics, isolation & purification)
• Mycobacterium Infections, Nontuberculous
• Positron-Emission Tomography
• Tomography, X-Ray Computed
• Whole Body Imaging