[A case report of distal gastrectomy with thrombectomy after NAC for Gastric cancer].

Abstract

This is a case report of gastric cancer with a tumor embolus in the portal vein of a 76-year-old male. Both computed tomography (CT) and upper gastrointestinal endoscopy were performed. The diagnosis was gastric cancer with an accompanying tumor embolus in the portal vein, specifically in the superior mesenteric vein. After neoadjuvant chemotherapy, a distal gastrectomy, and thrombectomy were performed. Upon pathological examination, the main tumor was diagnosed as adenocarcinoma, and the embolus was confirmed to extend from the main tumor into the superior mesenteric vein. Upon immunostaining examination, neither the embolus nor main tumor expressed alpha-fetoprotein (AFP), but both expressed carcinoembryonic antigen (CEA). Gastric cancer with a tumor embolus in the portal vein is considered an incurable disease. However, with no other non-curative factor than portal vein embolus, it is possible that gastrectomy with thrombectomy can result in a good prognosis. On the other hand, it is extremely difficult to improve the prognosis of gastric cancer with both tumor embolus in the portal vein and liver metastasis.

• Authors: Tomoyuki Nagata, Shozo Kitai, Yuzo Yamazato, Satoshi Mochizuki, Norio Ito, Yuen Nakase, Mitsuhiro Fujino, Seishirou Inaba
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 41 Issue 12 Pg. 2254-8 (Nov 2014) ISSN: 0385-0684 [Print] Japan
• PMID: 25731487 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Chemical References

• Drug Combinations
• S 1 (combination)
• Tegafur
• Oxonic Acid
• Cisplatin

Topics

• Adenocarcinoma (drug therapy, secondary, surgery)
• Aged
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Cisplatin (administration & dosage)
• Drug Combinations
• Embolism (etiology, surgery)
• Gastrectomy
• Humans
• Male
• Neoadjuvant Therapy
• Oxonic Acid (administration & dosage)
• Portal Vein (pathology)
• Stomach Neoplasms (complications, drug therapy, pathology, surgery)
• Tegafur (administration & dosage)
• Thrombectomy
• Tomography, X-Ray Computed