Abstract | BACKGROUND AND OBJECTIVE: MATERIALS AND METHODS: In this descriptive cross-sectional study, CSF of 100 children younger than 2 years of age with febrile convulsion was evaluated for detecting HHV-6 DNA by PCR. All of them were referred to emergency ward in Pediatric Medical Center from March 2010 to March 2011. General information, clinical manifestations, laboratory tests and outcomes were collected in the questionnaires. RESULTS: One hundred children including 59 males and 41 females were evaluated. HHV-6 was detected from CSF in six patients (6%) by PCR. Mean age was 8 months old. All children were younger than 12 months old. The most common primary manifestation was fever alone. None of them had rash. Majority of cases occurred in winter. All patients recovered without any encephalitis. CONCLUSION: These findings showed that primary infection with HHV-6 is frequently associated with febrile convulsion in infants which may be at risk for subsequent development of epilepsy.
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Authors | Setareh Mamishi, Laura Kamrani, Masoud Mohammadpour, Jila Yavarian |
Journal | Iranian journal of microbiology
(Iran J Microbiol)
Vol. 6
Issue 2
Pg. 87-90
(Apr 2014)
ISSN: 2008-3289 [Print] Iran |
PMID | 25705358
(Publication Type: Journal Article)
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